{"id":"W2546890812","doi":"10.1016/j.ebiom.2016.11.006","title":"Progranulin as a Novel Factor in Gaucher Disease","year":2016,"lang":"en","type":"letter","venue":"EBioMedicine","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"","keywords":"Lysosome; Glucocerebrosidase; Medicine; Chaperone (clinical); Lafora disease; Disease; Cancer research; Cell biology; Biology; Enzyme; Biochemistry; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000257976,0.0005994771,0.001045955,0.001085385,0.0000453063,0.00002554151,0.000407254,0.0008378729,0.005727441],"category_scores_gemma":[0.0007387244,0.0003886174,0.0002548514,0.0007740291,0.0004912753,0.00008065544,0.0001479676,0.002284356,0.001554836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005256508,"about_ca_system_score_gemma":0.0008124621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003048953,"about_ca_topic_score_gemma":0.00001081263,"domain_scores_codex":[0.9953353,0.00008065993,0.0006304958,0.000962751,0.001792714,0.00119811],"domain_scores_gemma":[0.997892,0.0001889891,0.0001464438,0.0009755207,0.0002143249,0.0005827241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006535015,0.0003590048,0.0101378,0.001426168,0.0001658217,0.01363556,0.0002108252,1.242458e-8,0.002067741,0.000007026899,0.9548005,0.01653601],"study_design_scores_gemma":[0.007188567,0.0005384433,0.01424684,0.002041387,0.0001117647,0.0001019546,0.00002269187,0.000009055067,0.00005388491,0.00009629208,0.9751636,0.000425482],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.009890031,0.002935423,0.0000793217,0.9783424,0.0005096653,0.002314722,0.0002324502,0.0001619373,0.005534019],"genre_scores_gemma":[0.02268172,0.0003230295,0.0002105692,0.8527908,0.01605165,0.0005523973,0.001911512,0.0003495094,0.1051288],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1255516,"threshold_uncertainty_score":0.9998566,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03700397311544799,"score_gpt":0.3361442161689607,"score_spread":0.2991402430535127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}