{"id":"W2546890850","doi":"10.1139/bcb-2016-0175","title":"Anticancer activities of bovine and human lactoferricin-derived peptides","year":2016,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Dalhousie University; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Peptide; Lactoferrin; Cytotoxicity; Cytotoxic T cell; Antimicrobial peptides; Cancer cell; Linker; In vitro; Biochemistry; Biology; Jurkat cells; Peptide sequence; Chemistry; Cancer; Immunology; Immune system; T cell; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006538216,0.0001559434,0.0002818045,0.0000290033,0.0001098261,0.000004866104,0.000077194,0.0002353286,0.0002464452],"category_scores_gemma":[0.00001624487,0.0001038877,0.00004248232,0.00002470698,0.001117139,0.00004351836,0.0001010179,0.00008196696,0.000004923244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008133516,"about_ca_system_score_gemma":0.00002115415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007828754,"about_ca_topic_score_gemma":0.000004648271,"domain_scores_codex":[0.9992924,0.00004245208,0.0001691363,0.0002611487,0.000009916684,0.0002248914],"domain_scores_gemma":[0.9995839,0.0001260135,0.0001123937,0.000135442,0.00002127484,0.00002097611],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009173697,0.00004448429,0.00639981,0.0000703783,0.00004530896,6.920217e-7,0.00006686571,6.984914e-9,0.9896803,0.0004522847,0.0004238457,0.002724253],"study_design_scores_gemma":[0.0006868243,0.0002071842,0.001842833,0.00004594585,0.00002321993,0.00001778295,0.0003391452,4.383382e-8,0.9930259,0.0001622779,0.003496091,0.000152744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.99471,0.002187174,0.00002887836,0.0001476538,0.00007052554,0.00005076034,0.00009228189,0.00002270224,0.00269004],"genre_scores_gemma":[0.9942254,0.0006361468,0.000037247,0.0000539019,0.00003761504,0.00000362191,0.00002493238,0.000008282216,0.004972868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004556977,"threshold_uncertainty_score":0.4236417,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008264504160439924,"score_gpt":0.222362868006026,"score_spread":0.2140983638455861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}