{"id":"W2546924190","doi":"10.1007/978-1-4939-6670-7_19","title":"Detection of Senescence Markers During Mammalian Embryonic Development","year":2016,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Senescence; Biology; Cell biology; Embryonic stem cell; Cellular senescence; Cyclin; Embryo; Cell; Cell growth; Cell cycle; In vitro; Phenotype; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005816455,0.0002060828,0.0002022949,0.0006519678,0.0002421998,0.000509721,0.0002389163,0.0003257447,0.0006176961],"category_scores_gemma":[0.0005304005,0.000250665,0.0001710891,0.0003071302,0.0003053303,0.000384496,0.0003002615,0.0006857772,0.0003444804],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002387458,"about_ca_system_score_gemma":0.0002385313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001843016,"about_ca_topic_score_gemma":0.0003857351,"domain_scores_codex":[0.9998302,0.00004040919,0.00001735626,0.00003536168,0.00004717686,0.00002937682],"domain_scores_gemma":[0.9997045,0.0001064105,0.00006096378,0.00003287648,0.00004619208,0.00004883325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001791145,0.00001243353,0.0007975307,0.00003619187,0.00000394856,0.00003733991,0.0000650236,0.0000300522,0.9942954,0.0003929235,0.00004560732,0.004104434],"study_design_scores_gemma":[0.00001717598,0.0002505236,0.01164504,0.00002053428,0.00002213503,0.0003264503,0.00005342818,0.0005427155,0.9803268,0.0003536654,0.006433328,0.000008284867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.9125534,0.022027,0.05901312,0.0002442189,0.00008964061,0.0000754284,0.0005915119,0.0002839407,0.005121714],"genre_scores_gemma":[0.9533914,0.007422057,0.02984888,0.0001730605,0.00006122822,0.0001356031,0.001161427,0.00007192293,0.007734384],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.0006519678,"threshold_uncertainty_score":0.003076077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01816036598467295,"score_gpt":0.3457502418287695,"score_spread":0.3275898758440965,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}