{"id":"W2547013708","doi":"10.1158/2326-6066.imm2016-a019","title":"Abstract A019: Chimeric antigen receptors (CARs) as a low-impact treatment of pediatric ependymomas","year":2016,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Ependymoma; Chimeric antigen receptor; Medicine; Oncology; Cancer research; Internal medicine; Antigen; Targeted therapy; Immunotherapy; Pathology; Immunology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000275973,0.000258649,0.0005959366,0.0006331936,0.0001262328,0.00001207626,0.0001926953,0.0002118772,0.004850588],"category_scores_gemma":[0.0001617639,0.0001455033,0.0002793823,0.0007105533,0.0003938969,0.00008234598,0.00006908794,0.0001825456,0.0007841805],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009819967,"about_ca_system_score_gemma":0.0009328244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002986633,"about_ca_topic_score_gemma":0.00004705214,"domain_scores_codex":[0.9977214,0.0001527593,0.0003729184,0.0004854174,0.0004542416,0.0008132618],"domain_scores_gemma":[0.9981837,0.0004364272,0.0001274494,0.0006818619,0.000355345,0.0002152088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001451702,0.002635485,0.6632177,0.00005120781,0.001927522,0.0006059146,0.0003934586,0.000001807175,0.1519825,0.00008104411,0.002289757,0.1753619],"study_design_scores_gemma":[0.005627249,0.004067724,0.837487,0.0001247163,0.0001180282,0.0001032627,0.00008914016,8.767466e-7,0.1473107,0.00007403748,0.00485283,0.0001444976],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9673249,0.02833436,6.039672e-7,0.001263313,0.0003070862,0.0007797816,0.00005504981,0.00003772258,0.001897182],"genre_scores_gemma":[0.9544801,0.04357942,0.00002467745,0.00001333072,0.0002695748,0.0003789366,0.00001836592,0.0000415508,0.001194042],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1752174,"threshold_uncertainty_score":0.9999938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07416632144904588,"score_gpt":0.4254098184673525,"score_spread":0.3512434970183066,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}