{"id":"W2547018141","doi":"10.1158/2326-6066.imm2016-b092","title":"Abstract B092: Therapeutic targeting of tumorigenic EphA2+/EphA3+ brain tumor initiating cells with bi-specific antibody in glioblastoma","year":2016,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster University","funders":"","keywords":"Cancer research; Erythropoietin-producing hepatocellular (Eph) receptor; EPH receptor A2; SOX2; Population; Biology; Brain tumor; Glioma; Medicine; Immunology; Receptor; Pathology; Internal medicine; Embryonic stem cell; Receptor tyrosine kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001406792,0.0002504372,0.0004123769,0.0005595463,0.000276634,0.00003686347,0.0008040833,0.0001065365,0.0005771104],"category_scores_gemma":[0.0004206716,0.000174706,0.00007398042,0.001294828,0.001089634,0.0003389503,0.0002036795,0.0008344554,0.0001209976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002148104,"about_ca_system_score_gemma":0.000431205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009162972,"about_ca_topic_score_gemma":0.00003380089,"domain_scores_codex":[0.9960365,0.0007215045,0.0006073453,0.0007949178,0.0006579257,0.001181781],"domain_scores_gemma":[0.9961247,0.002891786,0.0002570383,0.0004356026,0.0002090208,0.00008183972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008757855,0.00009958433,0.006466716,0.00003844935,0.00001450315,0.0002521872,0.0002773607,0.00002796321,0.986126,0.0003069061,0.00009321242,0.005421346],"study_design_scores_gemma":[0.001252983,0.0005651551,0.01321496,0.0004010715,0.00000243663,0.00002882828,0.0002333235,0.00002230506,0.9826571,0.0002368913,0.001164432,0.0002205546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994867,0.003139777,0.00007574225,0.0007428303,0.0002399674,0.0004217557,0.00002435104,0.00004979733,0.0004388327],"genre_scores_gemma":[0.9981532,0.001169981,0.0000271068,0.0002354,0.0001247829,0.0001001318,6.478206e-7,0.00005852929,0.0001302523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006748242,"threshold_uncertainty_score":0.7124305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08607020072303567,"score_gpt":0.3796350187056222,"score_spread":0.2935648179825865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}