{"id":"W2547018141","doi":"10.1158/2326-6066.imm2016-b092","title":"Abstract B092: Therapeutic targeting of tumorigenic EphA2+/EphA3+ brain tumor initiating cells with bi-specific antibody in glioblastoma","year":2016,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; McMaster University","funders":"","keywords":"Cancer research; Erythropoietin-producing hepatocellular (Eph) receptor; EPH receptor A2; SOX2; Population; Biology; Brain tumor; Glioma; Medicine; Immunology; Receptor; Pathology; Internal medicine; Embryonic stem cell; Receptor tyrosine kinase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001050385,0.0003460406,0.0003022455,0.0002345979,0.0001224191,0.0002497318,0.0001929703,0.000217567,0.0008676362],"category_scores_gemma":[0.00004685403,0.00009875678,0.0002039871,0.000184823,0.00009660565,0.00008995968,0.0001509112,0.000414251,0.000373356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002431273,"about_ca_system_score_gemma":0.000273113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001593907,"about_ca_topic_score_gemma":0.00206513,"domain_scores_codex":[0.9999264,0.000009137289,0.000006114627,0.00001150068,0.00002045576,0.00002628476],"domain_scores_gemma":[0.9999781,0.000002162796,0.000004756621,0.000002731852,0.000003632927,0.00000867901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001662942,0.0001185795,0.0001277469,0.00002829235,0.00001001171,0.0000408507,0.000007038984,0.0001183553,0.9962481,0.00008701768,0.000168173,0.002879613],"study_design_scores_gemma":[0.0001011409,0.001614085,0.005520622,0.000006064868,0.00005447113,0.0005273773,0.0000148744,0.0023532,0.9863712,0.00004727517,0.003383254,0.00000640703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934196,0.001340076,0.002244981,0.0001082513,0.00003935858,0.00009399919,0.0005823998,0.0001844472,0.001986903],"genre_scores_gemma":[0.9932339,0.0009624832,0.002567082,0.00007587136,0.00001106877,0.00008151252,0.0009115598,0.00002648894,0.002130109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001593907,"threshold_uncertainty_score":0.003169239,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08607020072303567,"score_gpt":0.3796350187056222,"score_spread":0.2935648179825865,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}