{"id":"W2547020086","doi":"10.1182/blood.v108.11.3720.3720","title":"Large-Scale Production of Autologous CD14+-Monocyte Derived Dendritic Cells Co-Electroporated with Amplified Total Tumour mRNA and Human CD40L mRNA in Patients with B-Cell Chronic Lymphocytic Leukemia.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Hamilton Health Sciences","funders":"","keywords":"Leukapheresis; CD14; Peripheral blood mononuclear cell; Medicine; CD20; Chronic lymphocytic leukemia; Dendritic cell; Immunology; ELISPOT; CD19; CD5; Immune system; Fludarabine; Antigen; Andrology; T cell; Leukemia; Biology; Internal medicine; Cyclophosphamide; CD34; In vitro; Chemotherapy; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000324641,0.0001975273,0.0002729326,0.0001032925,0.0001655576,0.0004179773,0.0001299013,0.0002412951,0.0008800509],"category_scores_gemma":[0.0003142441,0.0001434856,0.0001727207,0.000157215,0.0001604359,0.0001147904,0.0002360901,0.0004192755,0.0005018928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002223016,"about_ca_system_score_gemma":0.0002734303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002942115,"about_ca_topic_score_gemma":0.0002474696,"domain_scores_codex":[0.9998146,0.00005381915,0.0000123041,0.00004597942,0.00004046791,0.00003289864],"domain_scores_gemma":[0.9998969,0.00003167304,0.00001685219,0.00001958514,0.00001318856,0.0000218615],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.00172038,0.0006241974,0.004019867,0.00009957337,0.00001973149,0.0003705426,0.0001600761,0.0006263921,0.9765409,0.00009870535,0.0003465609,0.0153732],"study_design_scores_gemma":[0.002051067,0.02312038,0.03041467,0.00003535762,0.0001727742,0.003125577,0.0002577075,0.005874534,0.9234913,0.0001558544,0.01128072,0.00002013706],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969187,0.000393047,0.001799945,0.00005231868,0.00002051969,0.000167954,0.0001929713,0.00003002973,0.0004246242],"genre_scores_gemma":[0.9957855,0.000217821,0.002874931,0.0000454884,0.00001448311,0.0001063106,0.0004979803,0.00001027097,0.0004471489],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008800509,"threshold_uncertainty_score":0.002944112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003671635277657409,"score_gpt":0.1912685007987948,"score_spread":0.1875968655211374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}