{"id":"W2547136103","doi":"10.1182/blood.v118.21.1082.1082","title":"A Randomized Phase II Study Evaluating the Efficacy and Safety of Deferasirox Versus Deferoxamine in Patients with Sickle Cell Disease (SCD): 2-Year Results Including Pharmacokinetics (PK) and Safety of Deferasirox with Concomitant Hydroxyurea Therapy","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Deferasirox; Medicine; Deferoxamine; Concomitant; Adverse effect; Internal medicine; Gastroenterology; Surgery; Thalassemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003206514,0.001563122,0.003837887,0.0004449776,0.0005738266,0.001181419,0.0009368235,0.001682734,0.004861116],"category_scores_gemma":[0.002334262,0.0009463117,0.001817158,0.0004342354,0.001335195,0.001224991,0.0005145553,0.00335863,0.0009792019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001044386,"about_ca_system_score_gemma":0.001807073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008666971,"about_ca_topic_score_gemma":0.001972856,"domain_scores_codex":[0.9989146,0.0005697185,0.00005889926,0.0002091736,0.00009001558,0.0001575697],"domain_scores_gemma":[0.9976909,0.0004841716,0.0005500597,0.0002420555,0.0001754097,0.0008573448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9707117,0.01694356,0.0009944143,0.000171358,0.0004781364,0.00003879379,0.00004811901,0.000212914,0.004030112,0.00004037961,0.0003127524,0.006017754],"study_design_scores_gemma":[0.7668718,0.2289077,0.002743675,0.00001134866,0.0002605871,0.00004114319,0.00002204588,0.0002979962,0.000386156,0.00007031883,0.0003747894,0.0000124579],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913101,0.0014864,0.0004958469,0.0003351326,0.0002386485,0.004452959,0.000789191,0.00005942301,0.0008323782],"genre_scores_gemma":[0.985472,0.001152148,0.001936628,0.0008051724,0.000370186,0.006307062,0.001306336,0.00002249442,0.00262797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004861116,"threshold_uncertainty_score":0.01695782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0332366238534347,"score_gpt":0.2952136585262342,"score_spread":0.2619770346727995,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}