{"id":"W2547384253","doi":"10.1182/blood.v126.23.7.7","title":"A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Safety and Efficacy of Romiplostim in Children with Immune Thrombocytopenia (ITP)","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Romiplostim; Medicine; Placebo; Platelet; Internal medicine; Clinical endpoint; Randomized controlled trial; Adverse effect; Eltrombopag; Thrombopoietin; Surgery; Immune thrombocytopenia; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002565632,0.00121563,0.002961905,0.0003840055,0.0005888091,0.0009120709,0.0008682159,0.001994689,0.005437735],"category_scores_gemma":[0.001909807,0.0006219367,0.001473555,0.00044511,0.001171449,0.0008836376,0.0003088414,0.002838503,0.0007322968],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005901213,"about_ca_system_score_gemma":0.002078622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006627574,"about_ca_topic_score_gemma":0.001264771,"domain_scores_codex":[0.999171,0.0004380714,0.00006679528,0.0001389218,0.00008145621,0.0001036768],"domain_scores_gemma":[0.9985248,0.0004756846,0.0003928255,0.0001201848,0.0001232334,0.0003632604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.95092,0.01865314,0.00138239,0.001360086,0.001063326,0.0001276521,0.0000981679,0.0002624282,0.006562342,0.0001456795,0.001035861,0.01838892],"study_design_scores_gemma":[0.9248652,0.07273643,0.001464335,0.00002848319,0.0001588283,0.00003887154,0.00001156047,0.0001212425,0.0002651599,0.00004245185,0.0002615648,0.000005777298],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9795687,0.005686408,0.00110066,0.0005483843,0.0004303477,0.009779542,0.001261967,0.0001651724,0.001458847],"genre_scores_gemma":[0.9702672,0.003362735,0.003368035,0.00200396,0.0004710408,0.01757371,0.001186872,0.00003364858,0.001732935],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005437735,"threshold_uncertainty_score":0.01819104,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02335257347196919,"score_gpt":0.2978002481899081,"score_spread":0.274447674717939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}