{"id":"W2547437312","doi":"","title":"SGK1 (glucose transport), dishevelled2 (wnt signaling), LC3/p62 (autophagy) and p53 (apoptosis) proteins are unaltered in Lafora disease.","year":2016,"lang":"en","type":"article","venue":"PubMed","topic":"Glycogen Storage Diseases and Myoclonus","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Canada Research Chairs; Hospital for Sick Children","funders":"","keywords":"Lafora disease; Autophagy; Glycogen synthase; Glycogen; Neurodegeneration; Biology; GSK-3; Wnt signaling pathway; Cell biology; Endocrinology; Glucose transporter; GSK3B; Internal medicine; Kinase; Signal transduction; Apoptosis; Phosphorylation; Biochemistry; Phosphatase; Medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001851281,0.0005086826,0.0003289196,0.0006696322,0.0001888241,0.0003725185,0.0001445354,0.0003549522,0.002310725],"category_scores_gemma":[0.0001576969,0.000131487,0.0003048512,0.0002420527,0.0006102334,0.0003494579,0.0002716779,0.0003823145,0.000407701],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003358393,"about_ca_system_score_gemma":0.0002163488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004196707,"about_ca_topic_score_gemma":0.0008513461,"domain_scores_codex":[0.999864,0.00002534403,0.00002552522,0.00003436157,0.0000207824,0.0000300441],"domain_scores_gemma":[0.9998778,0.00001568701,0.00004024293,0.00001508389,0.000009299334,0.00004178808],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008609417,0.00003755411,0.004163165,0.0001085929,0.00003357914,0.0004890396,0.00004233926,0.00004008188,0.9889021,0.000241632,0.00008009769,0.005000836],"study_design_scores_gemma":[0.0000436144,0.0005556303,0.04688141,0.00001895153,0.00008705855,0.003021777,0.0001402056,0.0003507966,0.9458765,0.0003516295,0.002663309,0.000009093415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948534,0.001709528,0.001011507,0.0001341646,0.00002895034,0.00001150776,0.0004921132,0.00008583519,0.001672921],"genre_scores_gemma":[0.9963456,0.0006442394,0.0008574572,0.00004112403,0.000005243178,0.0000157313,0.0004993469,0.00001577399,0.001575479],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002310725,"threshold_uncertainty_score":0.007730126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0167051672981757,"score_gpt":0.2117219226466563,"score_spread":0.1950167553484806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}