{"id":"W2547495330","doi":"10.1139/cjc-2016-0462","title":"Branched-chain and dendritic lipids for nanoparticles","year":2016,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Lipophilicity; Conjugate; Drug delivery; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001749267,0.0004339344,0.0001576092,0.0003015522,0.0001866923,0.0002813374,0.0002829927,0.000410404,0.003702203],"category_scores_gemma":[0.0001917857,0.0001387177,0.0002472145,0.0002718704,0.000122675,0.0002865244,0.0004256475,0.000464329,0.00293038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004628903,"about_ca_system_score_gemma":0.0002775508,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002731914,"about_ca_topic_score_gemma":0.0005787825,"domain_scores_codex":[0.9998596,0.00001757768,0.00001411907,0.00003175258,0.00005418719,0.0000227647],"domain_scores_gemma":[0.9999298,0.000007300583,0.00001460931,0.000009435681,0.00002546142,0.00001331934],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008971831,0.00002837363,0.0000946432,0.0003027846,0.000009350351,0.0001075147,0.00002233523,0.0003189496,0.9791505,0.002685743,0.0008695494,0.01632038],"study_design_scores_gemma":[0.00002636018,0.0001296067,0.0002931776,0.00003020017,0.00001336874,0.0002870317,0.00001243333,0.001392373,0.9200652,0.0006135923,0.07712613,0.00001049601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.597421,0.05436895,0.2319897,0.003137111,0.001662404,0.001865454,0.006830039,0.00206561,0.1006598],"genre_scores_gemma":[0.8114915,0.02134104,0.1063182,0.001089024,0.0001486731,0.0008027439,0.004376336,0.0003321392,0.05410033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003702203,"threshold_uncertainty_score":0.01238507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00833741006959585,"score_gpt":0.2128647072617784,"score_spread":0.2045272971921825,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}