{"id":"W2547640677","doi":"10.1016/j.molmet.2016.10.011","title":"Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety","year":2016,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":251,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"FP7 Health; Division of Arctic Sciences; National Health and Medical Research Council; Australian Research Council; Biotechnology and Biological Sciences Research Council; Medical Research Council; Diabetes UK; Medical Research Council Canada; European Foundation for the Study of Diabetes; Fonds De La Recherche Scientifique - FNRS; European Research Council; University of Reading; Juvenile Diabetes Research Foundation United Kingdom; National Institute for Health and Care Research; Seventh Framework Programme","keywords":"Peptide YY; Enteroendocrine cell; Endocrinology; Carbohydrate; Internal medicine; Carbohydrate metabolism; Receptor; Appetite; Inulin; Biology; Hormone; Chemistry; Biochemistry; Neuropeptide; Endocrine system; Medicine; Neuropeptide Y receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001510651,0.000289747,0.0002669636,0.0001969744,0.0001165562,0.0002460055,0.0001383261,0.0002125663,0.002226796],"category_scores_gemma":[0.000113747,0.0001543198,0.0003655925,0.0001276727,0.0001974392,0.0001883153,0.0003274401,0.0006172718,0.0003616966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002083109,"about_ca_system_score_gemma":0.0001379701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004390761,"about_ca_topic_score_gemma":0.001115524,"domain_scores_codex":[0.9998771,0.00002426582,0.000009557752,0.00002486589,0.00002685236,0.00003744],"domain_scores_gemma":[0.9999039,0.0000141645,0.0000233363,0.00001412512,0.00000794189,0.00003649104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002326337,0.00002089958,0.0001660061,0.00001507582,0.000002597065,0.00002597453,0.000005636173,0.00001700432,0.9989624,0.00001610623,0.00001812929,0.0005175605],"study_design_scores_gemma":[0.00007450565,0.0008322579,0.02120476,0.00000863169,0.00001824179,0.0002497573,0.00007094038,0.0007573016,0.9748473,0.00004629921,0.001882846,0.000007220724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959649,0.001113796,0.001364521,0.0001182602,0.00003187274,0.00001540943,0.0002513585,0.00003157914,0.001108313],"genre_scores_gemma":[0.9930758,0.0007371811,0.002017978,0.0001119715,0.00002100204,0.00004371986,0.0003458821,0.00002654582,0.003619949],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002226796,"threshold_uncertainty_score":0.007449389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005008061625485199,"score_gpt":0.2309375417844571,"score_spread":0.2259294801589719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}