{"id":"W2547640677","doi":"10.1016/j.molmet.2016.10.011","title":"Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety","year":2016,"lang":"en","type":"article","venue":"Molecular Metabolism","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":251,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"FP7 Health; Division of Arctic Sciences; National Health and Medical Research Council; Australian Research Council; Biotechnology and Biological Sciences Research Council; Medical Research Council; Diabetes UK; Medical Research Council Canada; European Foundation for the Study of Diabetes; Fonds De La Recherche Scientifique - FNRS; European Research Council; University of Reading; Juvenile Diabetes Research Foundation United Kingdom; National Institute for Health and Care Research; Seventh Framework Programme","keywords":"Peptide YY; Enteroendocrine cell; Endocrinology; Carbohydrate; Internal medicine; Carbohydrate metabolism; Receptor; Appetite; Inulin; Biology; Hormone; Chemistry; Biochemistry; Neuropeptide; Endocrine system; Medicine; Neuropeptide Y receptor","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002709225,0.0003122573,0.0003071,0.00009239768,0.0001312609,0.00003837788,0.0003069217,0.0001753425,0.00008869872],"category_scores_gemma":[0.00004842169,0.0002428109,0.0001496434,0.0001457914,0.0000489187,0.00000771956,0.0003036178,0.00009697832,0.0001815431],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004795605,"about_ca_system_score_gemma":0.0001921506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003495121,"about_ca_topic_score_gemma":0.00005110578,"domain_scores_codex":[0.9979818,0.0001742728,0.0003294801,0.0006689983,0.0002230633,0.0006223335],"domain_scores_gemma":[0.9987108,0.00001071356,0.00009761278,0.0007010439,0.0001158541,0.0003639509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001124743,0.0001084628,0.0002978645,0.00001928695,0.00003685596,0.00001862516,0.000056695,0.00007628486,0.9960923,0.00008484676,0.002183577,0.0009127127],"study_design_scores_gemma":[0.001469514,0.0001588243,0.005231252,0.00002303793,0.00005987914,0.000008471574,0.00002252283,0.000007164478,0.932566,0.00007584171,0.06001143,0.000366051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933884,0.00249884,0.00182053,0.000749256,0.0003300856,0.0005289225,0.00007554368,0.00003410072,0.0005743409],"genre_scores_gemma":[0.9933257,0.0003873237,0.001128905,0.002405971,0.0001396648,0.00005834239,0.00007501886,0.00006443932,0.002414602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0635263,"threshold_uncertainty_score":0.9901541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005008061625485199,"score_gpt":0.2309375417844571,"score_spread":0.2259294801589719,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}