{"id":"W2547993878","doi":"10.1212/wnl.86.16_supplement.p3.266","title":"Clinical and Radiographic Improvement of Neurodegenerative Langerhans Cell Histiocytosis (ND-LCH) Following Dabrafenib (P3.266)","year":2016,"lang":"en","type":"article","venue":"Neurology","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Langerhans cell histiocytosis; Medicine; Histiocytosis; Radiography; Pathology; Dermatology; Radiology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002643225,0.0004395608,0.0004927292,0.000393761,0.0003361782,0.0003093967,0.0003689375,0.0007754727,0.0008355177],"category_scores_gemma":[0.0008211151,0.0002352894,0.0003399577,0.0002094597,0.0005003843,0.0002707625,0.0002548445,0.0009545325,0.00022178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000785274,"about_ca_system_score_gemma":0.0003651724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00343904,"about_ca_topic_score_gemma":0.007520088,"domain_scores_codex":[0.9997693,0.00003498546,0.00002525475,0.00006922702,0.00004656475,0.00005461543],"domain_scores_gemma":[0.9995272,0.00008068752,0.000127653,0.00002830891,0.00005695394,0.0001792593],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.003259737,0.0007672445,0.3873942,0.000351846,0.000261619,0.478676,0.001294122,0.001049921,0.06978375,0.0002821285,0.001868361,0.05501105],"study_design_scores_gemma":[0.0002814225,0.00364455,0.5253766,0.00004198537,0.0001159116,0.4570815,0.0002084448,0.0009477593,0.009708517,0.00006827342,0.002495014,0.00002996607],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995103,0.0007567445,0.0007749813,0.0003305644,0.00002316979,0.00009888251,0.0002572882,0.00006416986,0.002591242],"genre_scores_gemma":[0.9986718,0.0001521296,0.0005100985,0.00009774231,0.00001328671,0.00001168719,0.0001325844,0.000006709749,0.000404045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00343904,"threshold_uncertainty_score":0.006838024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01621831679156091,"score_gpt":0.2765142992203069,"score_spread":0.260295982428746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}