{"id":"W2548056002","doi":"10.1093/ofid/ofw172.1051","title":"Efficacy and Safety of Procalcitonin-Guided Decision Making in Neonates Suspected of Early Onset Sepsis: The Neopins Study—An International, Multicenter Non-Inferiority Randomized Controlled Intervention Trial","year":2016,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton; McMaster Children's Hospital","funders":"","keywords":"Medicine; Procalcitonin; Sepsis; Intervention (counseling); Randomized controlled trial; Intensive care medicine; Pediatrics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007683615,0.0002173388,0.001280664,0.0002077425,0.00008733541,0.00008679018,0.0002147183,0.00005747252,0.000174732],"category_scores_gemma":[0.002528943,0.0001085639,0.0003567522,0.0001584466,0.0001429174,0.0003048068,0.0002189591,0.00007169798,0.000002616546],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000127833,"about_ca_system_score_gemma":0.00008213984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001060508,"about_ca_topic_score_gemma":0.0007495383,"domain_scores_codex":[0.9976164,0.0004681225,0.001073758,0.0003367467,0.000320266,0.0001847203],"domain_scores_gemma":[0.996628,0.002141108,0.0005366968,0.0003479053,0.0002627076,0.00008355523],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.4510856,0.005167081,0.5355034,0.00001160296,0.0007009925,0.000006627659,0.0002480641,0.000003709006,0.00001734225,0.00005469407,0.00002359184,0.007177342],"study_design_scores_gemma":[0.5054123,0.001486243,0.4912408,0.0007474596,0.0004846697,0.000002443394,0.0001876056,0.000112895,0.00006986139,0.0001849125,0.000005416925,0.00006540716],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873009,0.0001431507,0.000137202,0.0003665496,0.000287571,0.01143966,0.00004107007,0.00002317418,0.0002606879],"genre_scores_gemma":[0.9985693,0.0001691583,0.00004630585,0.00006839623,0.00003188612,0.001059009,0.00001722669,0.00001873961,0.00002001923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05432674,"threshold_uncertainty_score":0.4427108,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03007486945221675,"score_gpt":0.3846518346549672,"score_spread":0.3545769652027504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}