{"id":"W2548056002","doi":"10.1093/ofid/ofw172.1051","title":"Efficacy and Safety of Procalcitonin-Guided Decision Making in Neonates Suspected of Early Onset Sepsis: The Neopins Study—An International, Multicenter Non-Inferiority Randomized Controlled Intervention Trial","year":2016,"lang":"en","type":"article","venue":"Open Forum Infectious Diseases","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton; McMaster Children's Hospital","funders":"","keywords":"Medicine; Procalcitonin; Sepsis; Intervention (counseling); Randomized controlled trial; Intensive care medicine; Pediatrics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004681994,0.001248482,0.002967612,0.0003568143,0.0003066936,0.001187169,0.0008950091,0.001401558,0.002212088],"category_scores_gemma":[0.009207255,0.0004404528,0.002759232,0.000335252,0.001227407,0.0008640947,0.0007103138,0.002167155,0.0002120919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009163896,"about_ca_system_score_gemma":0.001789255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004244128,"about_ca_topic_score_gemma":0.0005741448,"domain_scores_codex":[0.9967042,0.002457011,0.0002116592,0.0002937079,0.0002082538,0.0001252631],"domain_scores_gemma":[0.9949451,0.002272674,0.001583087,0.0003705203,0.0001958073,0.0006328608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.978028,0.002788255,0.001829103,0.001465441,0.002200355,0.00003916219,0.00005056185,0.0003478081,0.000623611,0.0001717999,0.0003568032,0.01209899],"study_design_scores_gemma":[0.946698,0.04473312,0.003721971,0.0003311603,0.002573955,0.00005017662,0.00003296926,0.0007379964,0.0003449919,0.0003576141,0.0003970355,0.0000209113],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829357,0.01085229,0.0007140584,0.001274656,0.0005478021,0.001825105,0.0004056204,0.00003585264,0.001408957],"genre_scores_gemma":[0.9870172,0.003838472,0.002309099,0.001021217,0.0004134219,0.004295557,0.0004541757,0.00001362877,0.0006370865],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004681994,"threshold_uncertainty_score":0.02476102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03007486945221675,"score_gpt":0.3846518346549672,"score_spread":0.3545769652027504,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}