{"id":"W2548161278","doi":"10.1158/2326-6066.imm2016-a068","title":"Abstract A068: Determinants of efficacy in cancer immunovirotherapy","year":2016,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Oncolytic virus; Medicine; Immune system; Immunotherapy; Antigen; Immunology; Melanoma; Cancer immunotherapy; Cancer research; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007539694,0.0002638839,0.0002960852,0.0004594526,0.0001413771,0.0006266877,0.0002167041,0.0005491336,0.003669513],"category_scores_gemma":[0.001017963,0.0001167556,0.0001936743,0.0002374745,0.0002656892,0.000370911,0.0002207539,0.0005748552,0.0008670721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003363369,"about_ca_system_score_gemma":0.0001773326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002679509,"about_ca_topic_score_gemma":0.0001447192,"domain_scores_codex":[0.9992477,0.0002694661,0.0000596228,0.00008487154,0.0002120396,0.0001263186],"domain_scores_gemma":[0.9989404,0.0005497232,0.0001544002,0.00005135903,0.0001626428,0.0001414056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001721258,0.0005689056,0.008062786,0.0001032725,0.00004281374,0.00006694969,0.0000498054,0.001079127,0.9665062,0.0005544638,0.0004165192,0.0208279],"study_design_scores_gemma":[0.0001192175,0.01392564,0.04747073,0.00004961827,0.00009467288,0.0009013591,0.0001246057,0.008879922,0.9216302,0.0006389253,0.006138827,0.0000263285],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929738,0.002488934,0.0008807626,0.00010545,0.00003390804,0.00005136056,0.0002505463,0.0000416777,0.003173625],"genre_scores_gemma":[0.9984745,0.0001788049,0.0004790972,0.00002852613,0.00001319697,0.00002429106,0.0001484144,0.00001019944,0.0006429253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003669513,"threshold_uncertainty_score":0.0122757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0705228761182105,"score_gpt":0.4335871343961777,"score_spread":0.3630642582779672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}