{"id":"W2548197444","doi":"10.1038/srep35465","title":"An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":121,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Defense Threat Reduction Agency; National Institutes of Health; Army Research Laboratory; Army Research Office; Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul; Conselho Nacional de Desenvolvimento Científico e Tecnológico; National Institute of Biomedical Imaging and Bioengineering; Fundación Ramón Areces","keywords":"Antimicrobial; Peptide; Antibiotics; Microbiology; Innate immune system; In vivo; Immune system; Antimicrobial peptides; Biology; Immunology; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006011138,0.0002978975,0.0003852658,0.0002088348,0.0007399755,0.000206501,0.0001151301,0.0001637638,0.0002748579],"category_scores_gemma":[0.00004063567,0.0001879693,0.00008436901,0.0001417313,0.002384146,0.0008293639,0.0001046718,0.0001642173,0.00006250866],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004961117,"about_ca_system_score_gemma":0.0001659264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009267384,"about_ca_topic_score_gemma":0.00004711619,"domain_scores_codex":[0.9979103,0.0001415744,0.0003401776,0.000974755,0.00008047486,0.0005527557],"domain_scores_gemma":[0.9986932,0.00009567717,0.0002918506,0.0007609981,0.0001035945,0.00005468642],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006392885,0.000137792,0.009553591,0.00001478034,0.0001004419,0.000135361,0.0004239747,0.000003879858,0.9832833,0.0001344963,0.003213234,0.002935246],"study_design_scores_gemma":[0.0005818839,0.0002151829,0.01272661,0.0001946888,0.00006202531,0.00401433,0.0004654239,7.240383e-7,0.9716412,0.0003513205,0.009270776,0.0004758789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956312,0.0001835584,0.0003038404,0.0001052883,0.002716228,0.0002595299,0.0000278831,0.0001511187,0.0006213638],"genre_scores_gemma":[0.9950988,0.00002052292,0.0001293743,0.00003792625,0.00004784067,0.00001110808,0.00003236974,0.00003456913,0.004587536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01164211,"threshold_uncertainty_score":0.8784485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005936843522857583,"score_gpt":0.2063236315306043,"score_spread":0.2003867880077467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}