{"id":"W2548197444","doi":"10.1038/srep35465","title":"An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":121,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Defense Threat Reduction Agency; National Institutes of Health; Army Research Laboratory; Army Research Office; Fundação de Apoio ao Desenvolvimento do Ensino, Ciência e Tecnologia do Estado de Mato Grosso do Sul; Conselho Nacional de Desenvolvimento Científico e Tecnológico; National Institute of Biomedical Imaging and Bioengineering; Fundación Ramón Areces","keywords":"Antimicrobial; Peptide; Antibiotics; Microbiology; Innate immune system; In vivo; Immune system; Antimicrobial peptides; Biology; Immunology; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001697872,0.0002977827,0.000193801,0.0001557466,0.00009205567,0.0003059428,0.0002136193,0.000344395,0.0006046082],"category_scores_gemma":[0.0001443439,0.00009327153,0.0001757419,0.0001154974,0.0002266208,0.0002297868,0.0002351661,0.0004489162,0.0001894103],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001521858,"about_ca_system_score_gemma":0.0001589944,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009565733,"about_ca_topic_score_gemma":0.0001750822,"domain_scores_codex":[0.999918,0.00001989825,0.000006023683,0.0000146418,0.00002197787,0.00001940134],"domain_scores_gemma":[0.9999133,0.00001355793,0.00002684683,0.000006358032,0.00001127184,0.00002854234],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006104414,0.00002559935,0.0001184719,0.00005565998,0.000004056847,0.00005635928,0.000006126245,0.0002114224,0.9950355,0.0001726984,0.00002518297,0.004227852],"study_design_scores_gemma":[0.00005075546,0.001653443,0.00230172,0.00002405351,0.00003308967,0.001122321,0.00001996025,0.001006254,0.9839102,0.0001319979,0.009735949,0.00001020717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9825177,0.0070719,0.007708949,0.0002180621,0.00006861603,0.00004485527,0.0001413689,0.00003637184,0.002192262],"genre_scores_gemma":[0.9836346,0.002607943,0.0116263,0.0001542438,0.00003886817,0.00003381882,0.000217803,0.00001096487,0.001675462],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006046082,"threshold_uncertainty_score":0.002022564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005936843522857583,"score_gpt":0.2063236315306043,"score_spread":0.2003867880077467,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}