{"id":"W2548323002","doi":"10.1158/2326-6066.imm2016-b053","title":"Abstract B053: Characterizing the effects of the DNA methylation inhibitor 5-AZA-CdR during CD8 T cell expansion","year":2016,"lang":"en","type":"article","venue":"Cancer Immunology Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Immunotherapy; Cancer immunotherapy; Cytotoxic T cell; Cancer research; Immune system; Immune checkpoint; DNA methylation; Immunology; CD8; Cancer; Biology; T cell; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001455451,0.0001595905,0.0001429599,0.0001004794,0.00007579922,0.0001881684,0.0001827374,0.0002235636,0.002200931],"category_scores_gemma":[0.0001053348,0.00006938256,0.0001405801,0.00008437962,0.00008510521,0.00009602894,0.00007010483,0.0005115694,0.0004240697],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001863464,"about_ca_system_score_gemma":0.0001268327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005770375,"about_ca_topic_score_gemma":0.0007053313,"domain_scores_codex":[0.9998779,0.00002091206,0.000007483908,0.00002633476,0.00003119628,0.00003610406],"domain_scores_gemma":[0.9999484,0.0000131595,0.00001067837,0.000004795944,0.00000794368,0.00001490645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004915644,0.0001287028,0.0001730991,0.00003068706,0.000005734227,0.00001588003,0.0000080933,0.000298333,0.9956341,0.00005248965,0.000120525,0.003040801],"study_design_scores_gemma":[0.00004814966,0.002387305,0.001797892,0.000003689832,0.0000146982,0.0000462526,0.000008017555,0.002061688,0.9920213,0.00002531846,0.001582729,0.000003032847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939452,0.001564473,0.001635589,0.00006308759,0.00004178477,0.0000442606,0.0004667623,0.00006528193,0.002173492],"genre_scores_gemma":[0.9960856,0.0002727457,0.001116589,0.00005693299,0.000008927664,0.00002670252,0.0004908593,0.00001356337,0.001928007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002200931,"threshold_uncertainty_score":0.007362843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.021777528994655,"score_gpt":0.3148692084796589,"score_spread":0.2930916794850039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}