{"id":"W2548747575","doi":"10.1016/j.bpj.2016.09.036","title":"Role of CBS and Bateman Domains in Phosphorylation-Dependent Regulation of a CLC Anion Channel","year":2016,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Phosphorylation; Cysteine; Chemistry; Ion channel; Intracellular; Mutant; Cell biology; Cytoplasm; Biochemistry; Biophysics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002247789,0.0002634864,0.0002256798,0.0001985307,0.0003698207,0.0004549328,0.0002723683,0.0003305322,0.00191019],"category_scores_gemma":[0.0003056067,0.0001527851,0.0002310396,0.0001072296,0.0004664079,0.0004988619,0.000373073,0.0006347876,0.000473617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003965138,"about_ca_system_score_gemma":0.0002984369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001010793,"about_ca_topic_score_gemma":0.001049285,"domain_scores_codex":[0.9998975,0.00001963377,0.00001120853,0.00002099644,0.00002406271,0.00002660503],"domain_scores_gemma":[0.9997061,0.00007515487,0.00006274773,0.00003107435,0.00003567755,0.00008927527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006225026,0.00001956346,0.0003554117,0.00002515056,0.000005063689,0.000168933,0.00003312714,0.0001288955,0.9966557,0.001048942,0.00005320476,0.0008834651],"study_design_scores_gemma":[0.00007446717,0.0001343081,0.01252341,0.000007313986,0.00001685932,0.0008627604,0.0001136713,0.003884937,0.9797698,0.0008745901,0.001715311,0.00002246314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959876,0.0006444044,0.002063176,0.0001810163,0.00002694949,0.000008933812,0.0000966525,0.00004506429,0.0009461284],"genre_scores_gemma":[0.9981237,0.0001460027,0.0007899576,0.00003446101,0.000007043613,0.000004592563,0.0001161048,0.00001358644,0.0007646094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00191019,"threshold_uncertainty_score":0.006390214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006786086814312215,"score_gpt":0.2213273408439245,"score_spread":0.2145412540296123,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}