{"id":"W2549180194","doi":"10.1182/blood.v108.11.356.356","title":"Aberrant Immunoglobulin Class Switch Recombination and Switch Translocations in Activated B Cell-Like Diffuse Large B-Cell Lymphoma.","year":2006,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Diffuse large B-cell lymphoma; Germinal center; Immunoglobulin class switching; Biology; Lymphoma; Chromosomal translocation; B cell; Large-cell lymphoma; Immunoglobulin heavy chain; Molecular biology; Cancer research; Antibody; Genetics; Gene; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002461753,0.0001651586,0.0001313616,0.0004910263,0.0001036475,0.0001855659,0.0000697872,0.0001941202,0.000739874],"category_scores_gemma":[0.0003422138,0.0001208611,0.0001046429,0.000191136,0.0002570371,0.00009858094,0.0001391975,0.0001757806,0.0001618631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001572952,"about_ca_system_score_gemma":0.00006555853,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003754819,"about_ca_topic_score_gemma":0.0005419765,"domain_scores_codex":[0.9998109,0.00004410856,0.00001580151,0.00004251064,0.00005164289,0.00003507106],"domain_scores_gemma":[0.999799,0.00005189876,0.0000593444,0.00002540289,0.00001712666,0.00004730463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005537057,0.00004166548,0.08669493,0.00004210214,0.00002457881,0.0009928793,0.0001044008,0.0001122658,0.9056097,0.0001514074,0.00005089397,0.005621361],"study_design_scores_gemma":[0.00009178721,0.00118326,0.8109996,0.000009235544,0.00007774539,0.02295753,0.0002339665,0.00196833,0.1591483,0.0004424255,0.002877722,0.00001020665],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991691,0.0001656664,0.0004190092,0.000006678538,0.000001023938,0.000003489035,0.0000302791,0.00001178205,0.0001929248],"genre_scores_gemma":[0.999572,0.00004848414,0.0001868848,0.000005385149,0.000001398584,0.000002207251,0.00007793112,0.000001703867,0.0001039781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000739874,"threshold_uncertainty_score":0.002475142,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00614617362832149,"score_gpt":0.2149629209912966,"score_spread":0.2088167473629751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}