{"id":"W2549387534","doi":"10.1371/journal.pone.0166621","title":"Characterization of a vraG Mutant in a Genetically Stable Staphylococcus aureus Small-Colony Variant and Preliminary Assessment for Use as a Live-Attenuated Vaccine against Intrammamary Infections","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Milk Quality and Mastitis in Dairy Cows","field":"Agricultural and Biological Sciences","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Staphylococcus aureus; Microbiology; Biology; Immune system; Virulence; Attenuated vaccine; Mutant; Phenotype; Bacteria; Immunology; Virology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002135747,0.0003408176,0.0003127008,0.0002049342,0.0001015772,0.0003102361,0.0003157637,0.0003699173,0.0004858417],"category_scores_gemma":[0.0002896421,0.00009578713,0.0004152026,0.000205099,0.0001541735,0.0001364651,0.0001798835,0.0005489526,0.0002725654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001463766,"about_ca_system_score_gemma":0.0001556134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001328756,"about_ca_topic_score_gemma":0.0008310684,"domain_scores_codex":[0.9998155,0.00003107485,0.00002632589,0.00003346254,0.00006115421,0.00003243558],"domain_scores_gemma":[0.9998211,0.0000389362,0.00004725685,0.00002520231,0.00003390196,0.00003372679],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004124658,0.00004807176,0.000107718,0.00001466439,0.000003960738,0.00005132891,0.00001261348,0.00008671446,0.9990975,0.00003005392,0.00001034159,0.0004958684],"study_design_scores_gemma":[0.00002091368,0.00155565,0.004014727,0.000009853798,0.00003230973,0.0004819692,0.00006419873,0.001744279,0.9902151,0.00002338725,0.001824929,0.00001259011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950725,0.0003805092,0.003491136,0.00005588444,0.0000247136,0.00006727772,0.0005324164,0.00002984909,0.000345667],"genre_scores_gemma":[0.990257,0.0003608311,0.00569991,0.00003217945,0.000007957789,0.00005178962,0.001828124,0.00004339326,0.001718775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001328756,"threshold_uncertainty_score":0.002642035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03975425032399333,"score_gpt":0.2296266368261938,"score_spread":0.1898723865022005,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}