{"id":"W2549403704","doi":"10.1182/blood.v126.23.267.267","title":"Ibrutinib Plus Bendamustine/Rituximab (BR) Is Associated with Greater Reductions in Fatigue Than Placebo Plus BR Among Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia and Fatigue","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Juravinski Cancer Centre","funders":"","keywords":"Medicine; Chemoimmunotherapy; Internal medicine; Bendamustine; Ibrutinib; Chronic lymphocytic leukemia; Placebo; Randomized controlled trial; Rituximab; Gastroenterology; Leukemia; Lymphoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007977813,0.0004433682,0.001406251,0.000244377,0.0001664771,0.0004003425,0.0002613308,0.0005852897,0.003120524],"category_scores_gemma":[0.0008775954,0.0002782808,0.0006761817,0.0001760089,0.0002400413,0.0005349449,0.0001827971,0.001109069,0.0004167944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002070768,"about_ca_system_score_gemma":0.0002661389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004395562,"about_ca_topic_score_gemma":0.0009709903,"domain_scores_codex":[0.9996706,0.0001489384,0.00003220177,0.00006459185,0.00003052928,0.00005312],"domain_scores_gemma":[0.9995961,0.0001071805,0.0001142132,0.00002720558,0.00001957941,0.0001359152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8268344,0.01190271,0.002909488,0.0009084346,0.001178008,0.00003982858,0.00009569809,0.0005223023,0.03142514,0.00005581754,0.001196787,0.1229314],"study_design_scores_gemma":[0.3821003,0.5506247,0.05686316,0.0001511594,0.00121769,0.0001859402,0.00007266291,0.0009532754,0.004660958,0.0001212984,0.003011756,0.00003711399],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992909,0.005468793,0.0001498088,0.0002008819,0.0001074099,0.0002104575,0.0002308448,0.00005800794,0.0006649629],"genre_scores_gemma":[0.9973155,0.001007266,0.0002546093,0.0002579569,0.00008885029,0.0001459381,0.000272614,0.000004716803,0.0006526002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003120524,"threshold_uncertainty_score":0.01043916,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03389796985584335,"score_gpt":0.2704612776565236,"score_spread":0.2365633078006802,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}