{"id":"W2549602975","doi":"10.1136/annrheumdis-2016-eular.3419","title":"SAT0002 Specific Premature Epigenetic Aging of Cartilage in Osteoarthritis","year":2016,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Medicine; Biomarker; Cartilage; Osteoarthritis; Epigenetics; Internal medicine; DNA methylation; Oncology; Bioinformatics; Pathology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002270206,0.0002895402,0.000203535,0.0002972622,0.0001930782,0.0003382639,0.0002799864,0.0004118369,0.00541182],"category_scores_gemma":[0.0002471174,0.0002000791,0.0003153747,0.0001838384,0.0003054013,0.0001489717,0.0002864242,0.0005630702,0.0006758238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001726371,"about_ca_system_score_gemma":0.0002425677,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004206981,"about_ca_topic_score_gemma":0.001048511,"domain_scores_codex":[0.9998621,0.00002674548,0.00001405045,0.0000307405,0.00003661563,0.00002971875],"domain_scores_gemma":[0.9998735,0.00001961122,0.00003688361,0.00001845386,0.00001370052,0.00003788159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006806875,0.00005258295,0.001644482,0.00008151704,0.00004341353,0.0003025966,0.00002161112,0.0001440293,0.9905986,0.0007871069,0.0005038313,0.005139537],"study_design_scores_gemma":[0.0002057804,0.001232984,0.08018281,0.00003035532,0.0002170611,0.004848781,0.0001720711,0.002520138,0.8940223,0.001175026,0.01536701,0.00002556896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9870132,0.00455304,0.002581172,0.0003626221,0.0002109764,0.00001916425,0.0007936747,0.0001621662,0.004304102],"genre_scores_gemma":[0.9948111,0.0006485788,0.0003829218,0.000124406,0.00001865962,0.00001447757,0.0005087448,0.00002738196,0.003463792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00541182,"threshold_uncertainty_score":0.01810437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01774342568824187,"score_gpt":0.2760575133497532,"score_spread":0.2583140876615113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}