{"id":"W2549755339","doi":"10.1002/eji.201646596","title":"B‐cell‐intrinsic function of TAPP adaptors in controlling germinal center responses and autoantibody production in mice","year":2016,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Medical Research Council; Institute of Infection and Immunity; Canadian Institutes of Health Research","keywords":"Germinal center; Autoantibody; Biology; B cell; Protein tyrosine phosphatase; Autoimmunity; Cell biology; Immune system; Antibody; T cell; Signal transduction; Molecular biology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001466347,0.0002081437,0.0005507901,0.000744482,0.00005811895,0.000006146299,0.0002496605,0.0001459672,0.0001074839],"category_scores_gemma":[0.0002985514,0.0001486092,0.00009741862,0.0001823103,0.0005037794,0.0001949883,0.0001009353,0.0005442461,0.00007800871],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006119033,"about_ca_system_score_gemma":0.00007925801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001914201,"about_ca_topic_score_gemma":0.00001267182,"domain_scores_codex":[0.9961934,0.002044751,0.0010637,0.0002727931,0.00004174948,0.000383575],"domain_scores_gemma":[0.9986008,0.0002920515,0.0007419917,0.0001967585,0.0001509223,0.0000175206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006234994,0.0003206724,0.01042766,0.00001448074,0.0001286682,0.0001050924,0.0004040416,0.000003455162,0.9616919,0.00006542901,0.0001728667,0.0204307],"study_design_scores_gemma":[0.01855233,0.004027552,0.2293187,0.000600451,0.00009371068,0.002682298,0.001058739,8.879229e-7,0.7255121,0.0001108105,0.01767033,0.0003720906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850843,0.0118836,0.0001449211,0.0005806516,0.001815922,0.0001346649,0.00000472584,0.00001337777,0.0003378393],"genre_scores_gemma":[0.9970423,0.001581643,0.00006278193,0.0000357368,0.00006290661,0.000001315606,0.000002964876,0.00002383338,0.001186514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2361798,"threshold_uncertainty_score":0.6060107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01018810316511109,"score_gpt":0.2086696085152661,"score_spread":0.198481505350155,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}