{"id":"W2550240482","doi":"10.1182/blood.v118.21.837.837","title":"A Randomized Trial of Sirolimus-Based Graft Versus Host Disease (GVHD) Prophylaxis After Hematopoietic Stem Cell Transplantation (HSCT) in Selected Patients with CR1 and CR2 ALL: Results From Children's Oncology Group Study ASCT0431","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of Manitoba","funders":"","keywords":"Medicine; Internal medicine; Sirolimus; Graft-versus-host disease; ThioTEPA; Hematopoietic stem cell transplantation; Transplantation; Regimen; Tacrolimus; Busulfan; Surgery; Gastroenterology; Randomization; Methotrexate; Cyclophosphamide; Oncology; Randomized controlled trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002831421,0.001531437,0.003054607,0.0004556392,0.0005212702,0.001108977,0.001013388,0.001493515,0.00349209],"category_scores_gemma":[0.002130931,0.0006499652,0.001821108,0.0005663194,0.001583537,0.0009444629,0.000566509,0.003440191,0.0005418463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001108642,"about_ca_system_score_gemma":0.002433196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001141718,"about_ca_topic_score_gemma":0.00263434,"domain_scores_codex":[0.9985506,0.0009768624,0.00007372714,0.0001596084,0.0000607199,0.0001785522],"domain_scores_gemma":[0.9975995,0.000616793,0.0005009807,0.0001976858,0.00009037424,0.0009946387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9844065,0.00532197,0.001551417,0.0001111597,0.0004157573,0.00003924565,0.00003427732,0.0003066991,0.001709675,0.00009288025,0.0003281877,0.005682195],"study_design_scores_gemma":[0.8691142,0.1268273,0.002764587,0.00001255195,0.0002431721,0.0000357694,0.00001614896,0.0002995898,0.0002827663,0.00009069405,0.0003033539,0.000009858534],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995396,0.001020118,0.0002157324,0.000475817,0.0002154197,0.001647938,0.0004081111,0.00004049743,0.0005804866],"genre_scores_gemma":[0.9936059,0.0007007861,0.0009170304,0.0007195079,0.0003212973,0.001940529,0.0008945863,0.00001462921,0.0008856514],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00349209,"threshold_uncertainty_score":0.01497412,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0123817906148278,"score_gpt":0.2419594147042131,"score_spread":0.2295776240893853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}