{"id":"W2550294901","doi":"10.1182/blood.v122.21.4840.4840","title":"Optimization Of Stepwise Hematopoietic Differentiation Of Human iPSCs","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"KLF4; Induced pluripotent stem cell; SOX2; Haematopoiesis; Biology; Stem cell; Small hairpin RNA; Cell biology; Cellular differentiation; Regenerative medicine; Molecular biology; Cell culture; Embryonic stem cell; Genetics; Gene knockdown","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001072111,0.000734435,0.0006006878,0.0005185837,0.0002682554,0.0007132327,0.0005028314,0.0004196401,0.001688547],"category_scores_gemma":[0.0006297088,0.0002548569,0.0005082985,0.0005831784,0.0002210087,0.0001737882,0.0005935712,0.0007397442,0.001090934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002862208,"about_ca_system_score_gemma":0.0003804349,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006976793,"about_ca_topic_score_gemma":0.001120043,"domain_scores_codex":[0.9992331,0.0001536104,0.000176097,0.0001255916,0.0002140646,0.0000976082],"domain_scores_gemma":[0.9996469,0.00008893153,0.00005064069,0.00005996893,0.0001084143,0.00004507334],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001295315,0.0001097528,0.0004733184,0.0001479679,0.00002024089,0.0001612461,0.00007571426,0.001361819,0.9896865,0.0001781125,0.0002710917,0.007384588],"study_design_scores_gemma":[0.00001830527,0.0002582419,0.001680579,0.00003081678,0.00005528229,0.0001294444,0.00003861005,0.001551265,0.9889737,0.00005175699,0.007198512,0.0000134482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.911877,0.006019911,0.06173681,0.0002244397,0.0002383861,0.002168756,0.003874874,0.000709481,0.01315039],"genre_scores_gemma":[0.9195138,0.004075678,0.06196384,0.0002111766,0.00004167227,0.001428193,0.007295388,0.0003139289,0.005156221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001688547,"threshold_uncertainty_score":0.005669892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01010557559390579,"score_gpt":0.2431139095580884,"score_spread":0.2330083339641826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}