{"id":"W2550346556","doi":"10.1016/j.jmb.2022.167515","title":"RBPBind: Quantitative Prediction of Protein-RNA Interactions","year":2022,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"University of Toronto; National Science Foundation","keywords":"RNA; Computational biology; RNA-binding protein; Biology; Riboswitch; Binding site; Sequence (biology); Messenger RNA; Genetics; Non-coding RNA; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001698289,0.001719964,0.001300344,0.001658361,0.000522751,0.0009973547,0.001805553,0.001018384,0.006120828],"category_scores_gemma":[0.003706437,0.000796064,0.0009557792,0.0009504686,0.0004174437,0.0008504822,0.0007071485,0.00141683,0.002737818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005368057,"about_ca_system_score_gemma":0.0006967729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001225052,"about_ca_topic_score_gemma":0.001766904,"domain_scores_codex":[0.9991804,0.0001952931,0.00004252396,0.0002517106,0.0002680959,0.00006197474],"domain_scores_gemma":[0.998455,0.001023491,0.0001491101,0.0001610502,0.0001217313,0.00008948982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.006804328,0.0009907455,0.01751028,0.001749349,0.0007300511,0.0006241424,0.0001387934,0.1100617,0.5245579,0.01063312,0.04571411,0.2804855],"study_design_scores_gemma":[0.000223953,0.0003052897,0.00532593,0.00002082877,0.00007521638,0.0003276319,0.0000192053,0.8783848,0.1056673,0.005149896,0.004439062,0.00006094938],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1765971,0.0007556978,0.6915733,0.0002276556,0.0001272387,0.0002277985,0.01821471,0.1094682,0.002808354],"genre_scores_gemma":[0.5047649,0.0002636905,0.464831,0.0001711696,0.00007711128,0.0007018954,0.02117659,0.005191137,0.002822565],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.006120828,"threshold_uncertainty_score":0.02047622,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01684095938567731,"score_gpt":0.2873755485191652,"score_spread":0.2705345891334879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}