{"id":"W2550461848","doi":"10.1183/13993003.congress-2016.oa3342","title":"Afatinib (A) vs gefitinib (G) as first-line treatment (tx) for patients (pts) with<i>EGFR</i>mutation-positive (<i>EGFR</i>m+) NSCLC: LUX-Lung 7","year":2016,"lang":"en","type":"article","venue":"","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; Internal medicine; Afatinib; Discontinuation; Gefitinib; Rash; Lung cancer; Clinical endpoint; Gastroenterology; Adverse effect; Oncology; Randomized controlled trial; Cancer; Epidermal growth factor receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001425579,0.0006337056,0.001482542,0.0003436312,0.0002351423,0.0006744643,0.0004929317,0.001225925,0.004895414],"category_scores_gemma":[0.001653043,0.0003432802,0.002112005,0.0002831989,0.0005262432,0.0007689804,0.0003403675,0.001835507,0.0005504356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008462694,"about_ca_system_score_gemma":0.0008892578,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008521882,"about_ca_topic_score_gemma":0.002027407,"domain_scores_codex":[0.9994463,0.0003086142,0.00005877553,0.00007401924,0.00003456471,0.00007771322],"domain_scores_gemma":[0.9991186,0.0002931046,0.0002310649,0.00003623733,0.00003246379,0.0002884595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9741712,0.001718921,0.001081414,0.0003698956,0.0007567349,0.00003041644,0.00003216233,0.0004763023,0.001921708,0.00009046597,0.0007356912,0.01861513],"study_design_scores_gemma":[0.6971625,0.2879126,0.008110164,0.0001008489,0.001779219,0.0001622719,0.00006036822,0.001413109,0.001266077,0.0003575728,0.001642091,0.00003317231],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.989922,0.005400483,0.0002340926,0.0008396027,0.0004756247,0.0007208788,0.0006923721,0.00004851003,0.001666549],"genre_scores_gemma":[0.9954734,0.001672853,0.0002889651,0.0004152258,0.0002550974,0.000460273,0.0004023044,0.000006916368,0.001024829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004895414,"threshold_uncertainty_score":0.01637679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01042698693705084,"score_gpt":0.3057259158266201,"score_spread":0.2952989288895692,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}