{"id":"W2550484150","doi":"10.1136/annrheumdis-2016-eular.3590","title":"FRI0446 Treatment with Tildrakizumab, An Anti-IL-23P19 Monoclonal Antibody, Improves Health-Related Quality of Life in Patients with Chronic Plaque Psoriasis","year":2016,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University; Probity Medical Research","funders":"","keywords":"Medicine; Dermatology Life Quality Index; Psoriasis; Psoriasis Area and Severity Index; Quality of life (healthcare); Internal medicine; Placebo; Physical therapy; Gastroenterology; Dermatology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002748488,0.0003438064,0.00109401,0.0002188242,0.0002428684,0.000341898,0.000219984,0.0003188137,0.00177537],"category_scores_gemma":[0.0003538625,0.0001248318,0.0006818385,0.0001865007,0.0001252085,0.0002432363,0.0001429965,0.0006864073,0.0004172064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001702072,"about_ca_system_score_gemma":0.0001941334,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000654594,"about_ca_topic_score_gemma":0.001391768,"domain_scores_codex":[0.9998567,0.00004149247,0.00001444742,0.00001633289,0.00002985918,0.00004108564],"domain_scores_gemma":[0.9998748,0.00002306074,0.00003736714,0.00000916831,0.00001035597,0.00004519274],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0880858,0.009924583,0.02674028,0.001545129,0.00206198,0.00107083,0.0001974193,0.0007651911,0.1684626,0.0001393956,0.009082087,0.6919246],"study_design_scores_gemma":[0.04590005,0.1445231,0.7210227,0.0003299176,0.00330072,0.008651916,0.0004362753,0.004216076,0.0493371,0.0004542227,0.02171336,0.0001144668],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762772,0.0200566,0.0004107482,0.0005304027,0.0002062765,0.00006991991,0.0002826907,0.0001762949,0.001990016],"genre_scores_gemma":[0.9951467,0.002845711,0.0005136965,0.0002552134,0.0001304372,0.00003088559,0.0002972064,0.000008896015,0.0007710789],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00177537,"threshold_uncertainty_score":0.005939245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0298097574819122,"score_gpt":0.2868373016328367,"score_spread":0.2570275441509245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}