{"id":"W2550524043","doi":"10.1182/blood.v118.21.2859.2859","title":"Interim Results for the Safety and Efficacy of Different Lenalidomide Starting Dose Regimens in Subjects with Relapsed or Refractory Chronic Lymphocytic Leukemia (CC-5013-CLL-009 Study)","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Lenalidomide; Medicine; Tolerability; Bendamustine; Regimen; Internal medicine; Chronic lymphocytic leukemia; Interim analysis; Refractory (planetary science); Tumor lysis syndrome; Neutropenia; Oncology; Clinical trial; Pharmacology; Adverse effect; Leukemia; Chemotherapy; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001149411,0.0003601143,0.0007716722,0.0002141972,0.0001302176,0.00002444627,0.0003131351,0.0001429019,0.00001710089],"category_scores_gemma":[0.001344413,0.0002006342,0.00009996665,0.0003753831,0.0002704003,0.0001034981,0.0002113474,0.0003748761,0.000004415206],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.01643661,"about_ca_system_score_gemma":0.01207211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002361442,"about_ca_topic_score_gemma":0.002506041,"domain_scores_codex":[0.9969175,0.0002066834,0.0009573163,0.000663153,0.0005669866,0.0006883066],"domain_scores_gemma":[0.9963036,0.001897235,0.0003720185,0.001061606,0.0001631761,0.0002023409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7597957,0.03707135,0.01422392,0.006579642,0.007283685,0.004694715,0.1047647,0.0003329926,0.03642556,0.0005864363,0.001079536,0.02716181],"study_design_scores_gemma":[0.8681589,0.01658103,0.06310086,0.002205731,0.001282619,0.0003118077,0.003745079,0.006250798,0.03753533,0.00003311194,0.0002568681,0.000537836],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951984,0.0008036809,0.00003247334,0.00006228629,0.00006892632,0.003130251,0.0000125989,0.00005713433,0.0006341912],"genre_scores_gemma":[0.9983994,0.0003078739,0.0002245846,0.00005235764,0.0001321308,0.00014436,0.00001272795,0.00007096719,0.0006555877],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1083632,"threshold_uncertainty_score":0.9935285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04687574105657977,"score_gpt":0.3025787118389563,"score_spread":0.2557029707823765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}