{"id":"W2550524043","doi":"10.1182/blood.v118.21.2859.2859","title":"Interim Results for the Safety and Efficacy of Different Lenalidomide Starting Dose Regimens in Subjects with Relapsed or Refractory Chronic Lymphocytic Leukemia (CC-5013-CLL-009 Study)","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Juravinski Cancer Centre","funders":"","keywords":"Lenalidomide; Medicine; Tolerability; Bendamustine; Regimen; Internal medicine; Chronic lymphocytic leukemia; Interim analysis; Refractory (planetary science); Tumor lysis syndrome; Neutropenia; Oncology; Clinical trial; Pharmacology; Adverse effect; Leukemia; Chemotherapy; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0115059,0.0009061336,0.001599179,0.0004381819,0.0003310507,0.001316249,0.0007789629,0.001240519,0.00661686],"category_scores_gemma":[0.005555352,0.0004510276,0.002783239,0.0004495607,0.0003691723,0.0006985185,0.000548634,0.001786755,0.001291577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007880586,"about_ca_system_score_gemma":0.00127942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008324177,"about_ca_topic_score_gemma":0.00149768,"domain_scores_codex":[0.9968275,0.002149997,0.0001417949,0.0003424407,0.0002972173,0.0002409886],"domain_scores_gemma":[0.9954063,0.002094912,0.00115744,0.0005555933,0.0002822797,0.0005035275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8725682,0.00489275,0.03246161,0.0005719595,0.005278926,0.0001355172,0.00007531037,0.006134794,0.007839303,0.0004231841,0.01144208,0.05817636],"study_design_scores_gemma":[0.4630222,0.25542,0.2304724,0.000225599,0.01216771,0.0004640475,0.0000751754,0.01101054,0.01011895,0.00159293,0.01526452,0.0001659763],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9324583,0.005238628,0.005022215,0.001117621,0.0002278281,0.005423801,0.0373491,0.0005647482,0.01259756],"genre_scores_gemma":[0.9403486,0.0008582248,0.005725289,0.001266879,0.0001532943,0.004733027,0.04164545,0.0001380806,0.005131323],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0115059,"threshold_uncertainty_score":0.06084973,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04687574105657977,"score_gpt":0.3025787118389563,"score_spread":0.2557029707823765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}