{"id":"W2550547063","doi":"10.1159/000448957","title":"Gut Microbiota, Bacterial Translocation, and Interactions with Diet: Pathophysiological Links between Major Depressive Disorder and Non-Communicable Medical Comorbidities","year":2016,"lang":"en","type":"review","venue":"Psychotherapy and Psychosomatics","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":276,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; University Health Network; University of Toronto; McMaster University","funders":"National Health and Medical Research Council; Medical Research Council; Centro de Investigación Biomédica en Red de Salud Mental; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Instituto de Salud Carlos III; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Stanley Medical Research Institute","keywords":"Irritable bowel syndrome; Pathophysiology; Dysbiosis; Gut–brain axis; Major depressive disorder; Gut flora; Medicine; Chronic fatigue syndrome; Microbiome; Internal medicine; Endocrinology; Immunology; Bioinformatics; Biology; Amygdala","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009444107,0.0002938742,0.001344379,0.005016983,0.0003087593,0.0009186951,0.000432143,0.0009372132,0.003102877],"category_scores_gemma":[0.003249366,0.0001929076,0.0009222202,0.01004885,0.0004381715,0.0007949819,0.0005602783,0.0003169898,0.0002647409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007595916,"about_ca_system_score_gemma":0.002096054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003710957,"about_ca_topic_score_gemma":0.01207815,"domain_scores_codex":[0.9993699,0.0001569085,0.000273067,0.0000664535,0.0001008268,0.00003291118],"domain_scores_gemma":[0.9965233,0.001906912,0.001308466,0.00003504469,0.0001570289,0.00006908958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001282088,0.0001143027,0.1260602,0.5962086,0.004213985,0.003394087,0.001308186,0.0003169326,0.002501756,0.001622053,0.01076064,0.2522172],"study_design_scores_gemma":[0.0003972771,0.0006889693,0.5875378,0.2854226,0.01479214,0.01069043,0.00252613,0.0003961565,0.0008026442,0.002349856,0.09429342,0.0001025813],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0267529,0.9681668,0.0001494052,0.001148826,0.0001328734,0.0001297697,0.002042875,0.000007467693,0.001468999],"genre_scores_gemma":[0.1503886,0.8446698,0.001370488,0.001445011,0.0002384206,0.0002422239,0.001211849,0.000003596704,0.000430049],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005016983,"threshold_uncertainty_score":0.01038015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01988682336482693,"score_gpt":0.3276683983403066,"score_spread":0.3077815749754796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}