{"id":"W2550547063","doi":"10.1159/000448957","title":"Gut Microbiota, Bacterial Translocation, and Interactions with Diet: Pathophysiological Links between Major Depressive Disorder and Non-Communicable Medical Comorbidities","year":2016,"lang":"en","type":"review","venue":"Psychotherapy and Psychosomatics","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":276,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Joseph’s Healthcare Hamilton; University Health Network; University of Toronto; McMaster University","funders":"National Health and Medical Research Council; Medical Research Council; Centro de Investigación Biomédica en Red de Salud Mental; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Instituto de Salud Carlos III; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Stanley Medical Research Institute","keywords":"Irritable bowel syndrome; Pathophysiology; Dysbiosis; Gut–brain axis; Major depressive disorder; Gut flora; Medicine; Chronic fatigue syndrome; Microbiome; Internal medicine; Endocrinology; Immunology; Bioinformatics; Biology; Amygdala","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001462898,0.0004668837,0.0009893005,0.00005636154,0.000260497,0.0000743296,0.0002488775,0.0008228462,0.00009231213],"category_scores_gemma":[0.000006600059,0.00027668,0.0001093682,0.00006910748,0.0003514318,0.00001040428,0.00003585916,0.0004808128,0.000003966265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007124105,"about_ca_system_score_gemma":0.00009617679,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000156129,"about_ca_topic_score_gemma":0.0001292484,"domain_scores_codex":[0.9983107,0.0002186329,0.0005381741,0.0005367532,0.00009778109,0.0002979471],"domain_scores_gemma":[0.9988755,0.0001576196,0.0002740989,0.0004346684,0.00004705063,0.00021109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003910718,0.0002644647,0.0003639407,0.004551538,0.0008527637,0.000002766448,0.0004552172,1.649501e-8,0.0123249,0.00003048357,0.00156759,0.9791952],"study_design_scores_gemma":[0.00189831,0.0007201432,0.001255957,0.006620905,0.0001712912,0.0001000257,0.0000311413,0.00000111169,0.00002040082,0.0001476718,0.9884976,0.0005354968],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03950987,0.9572791,0.001116431,0.0005646258,0.0002030477,0.0007866127,0.0004481789,0.00001721978,0.00007489432],"genre_scores_gemma":[0.00161223,0.9958425,0.0009611561,0.0002577158,0.0004785712,0.0001012657,0.0005664219,0.00004755365,0.0001326154],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.98693,"threshold_uncertainty_score":0.9999685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01988682336482693,"score_gpt":0.3276683983403066,"score_spread":0.3077815749754796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}