{"id":"W2550562105","doi":"10.1182/blood.v124.21.4186.4186","title":"Genotype Phenotype Correlation in Patients with aHUS and Abnormal Genetic Studies: A Single Centre Experience","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Atypical hemolytic uremic syndrome; Eculizumab; Thrombotic microangiopathy; Medicine; Factor H; Internal medicine; Gastroenterology; Complement system; Creatinine; Immunology; Antibody; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005327874,0.0005901598,0.0006261601,0.00131784,0.0008774725,0.0007623673,0.0004308219,0.0007380645,0.002348795],"category_scores_gemma":[0.003555556,0.0005305247,0.0003919052,0.001022916,0.0006605689,0.0005102548,0.000779062,0.0005720442,0.0004253237],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004325107,"about_ca_system_score_gemma":0.0004669233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002313926,"about_ca_topic_score_gemma":0.00164765,"domain_scores_codex":[0.9990388,0.0002266476,0.0001262361,0.0002432346,0.0001818417,0.0001832424],"domain_scores_gemma":[0.9978032,0.0006601595,0.0005778502,0.0001728529,0.0001901699,0.0005957713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001498405,0.0001784989,0.9480964,0.0000250677,0.00002890962,0.04579915,0.0008775509,0.00006678837,0.0008353238,0.00005379859,0.0002025804,0.003686251],"study_design_scores_gemma":[0.00005617281,0.00104597,0.7256275,0.00005074873,0.00005860661,0.2688783,0.002060354,0.0006435827,0.0006588244,0.0001490991,0.0007228291,0.00004797787],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990453,0.0002145872,0.0001753379,0.00002988242,0.00000814477,0.00001422513,0.00003862867,0.000006546123,0.0004673416],"genre_scores_gemma":[0.9997004,0.00006810748,0.0001011662,0.0000241303,0.00001406926,0.000003581556,0.00002958289,0.000003391971,0.00005566611],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002348795,"threshold_uncertainty_score":0.007857442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009791142084565845,"score_gpt":0.2131994854730464,"score_spread":0.2034083433884805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}