{"id":"W2550562105","doi":"10.1182/blood.v124.21.4186.4186","title":"Genotype Phenotype Correlation in Patients with aHUS and Abnormal Genetic Studies: A Single Centre Experience","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Complement system in diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Atypical hemolytic uremic syndrome; Eculizumab; Thrombotic microangiopathy; Medicine; Factor H; Internal medicine; Gastroenterology; Complement system; Creatinine; Immunology; Antibody; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000428053,0.0001009446,0.0001450577,0.00004480688,0.00007059055,0.000007236102,0.00006781805,0.00004215986,0.0000838598],"category_scores_gemma":[0.0000617574,0.00008343541,0.00001106573,0.00006850244,0.0000790857,0.00004907716,0.00005445258,0.00004794994,0.000048613],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001607118,"about_ca_system_score_gemma":0.000009662213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002086458,"about_ca_topic_score_gemma":0.00008654248,"domain_scores_codex":[0.9993197,0.00009694516,0.0001652891,0.0001984076,0.00003325075,0.0001863827],"domain_scores_gemma":[0.9996401,0.00006928061,0.0000707561,0.0001509255,0.00005385735,0.00001507693],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009483722,0.0004040722,0.9949494,0.00002157059,0.00005897908,0.000001029072,0.00218069,0.00001418562,0.00101376,0.00004520173,0.00005722652,0.001159075],"study_design_scores_gemma":[0.004149384,0.0003561867,0.993551,0.00006313441,0.00005389441,0.000002254909,0.0005239031,0.000006800882,0.0005870192,0.00002495933,0.000551324,0.0001301869],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975203,0.001838089,0.00004197919,0.00001047966,0.0001561713,0.0002455755,0.00000642426,0.00002530751,0.0001556323],"genre_scores_gemma":[0.9997286,0.000004897812,0.0001071715,0.00003008331,0.00001342201,0.00001351343,0.00002714733,0.000007895897,0.00006731494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004054547,"threshold_uncertainty_score":0.3402397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009791142084565845,"score_gpt":0.2131994854730464,"score_spread":0.2034083433884805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}