{"id":"W2550863734","doi":"10.1182/blood.v114.22.1698.1698","title":"Hypoxia Inducible Factor 1a (HIF-1a) Regulates CD20 Expression in Lymphoma Cells: Possible Implications for Rituximab Based Therapy in Diffuse Large B Cell Lymphoma (DLBCL).","year":2009,"lang":"en","type":"article","venue":"Blood","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"CHOP; Lymphoma; Cancer research; Diffuse large B-cell lymphoma; Follicular lymphoma; Rituximab; CD20; Internal medicine; Angiogenesis; Medicine; BCL10; Biology; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002443057,0.0001364044,0.0002105465,0.0001443468,0.00012339,0.0003246302,0.0001947257,0.0003612663,0.002908489],"category_scores_gemma":[0.0001630848,0.00008121981,0.0001591409,0.0001593661,0.0001935118,0.0002211832,0.0001310439,0.000283944,0.0003562484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003684709,"about_ca_system_score_gemma":0.0001171959,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002549021,"about_ca_topic_score_gemma":0.0003004803,"domain_scores_codex":[0.9999336,0.00002117948,0.000003075699,0.000009661828,0.000009968518,0.00002247049],"domain_scores_gemma":[0.9999589,0.000008278284,0.00001037417,0.000001852399,0.000005960657,0.00001464095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003578526,0.0004500736,0.01377812,0.0007241005,0.00005284239,0.001422227,0.0001372847,0.0002673072,0.8978231,0.001139004,0.004312965,0.07631439],"study_design_scores_gemma":[0.001074711,0.007582487,0.5090042,0.00025628,0.0004174763,0.0093059,0.0009056944,0.006191586,0.3635983,0.002333414,0.09927934,0.00005057578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9046034,0.08145484,0.001359613,0.002354343,0.0002649917,0.00009470953,0.0003680925,0.00007392054,0.009426156],"genre_scores_gemma":[0.9869006,0.009318843,0.00048628,0.0003671427,0.0001330182,0.00004926501,0.0002524223,0.00000844517,0.002483855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002908489,"threshold_uncertainty_score":0.009729922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01294300940505879,"score_gpt":0.2495821076815632,"score_spread":0.2366390982765044,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}