{"id":"W2551042557","doi":"10.1182/blood.v118.21.227.227","title":"Mutated EZH2 Collaborates with Myc in Inducing Lymphoma in a Mouse Model","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Cancer Agency","funders":"","keywords":"EZH2; Lymphoma; Germinal center; Cancer research; Biology; Transgene; Follicular lymphoma; Genetically modified mouse; Spleen; Molecular biology; Immunology; B cell; Genetics; Antibody; Histone; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004927625,0.0009719228,0.000603525,0.001364401,0.0002843769,0.0005577341,0.0005877709,0.0009316372,0.001582581],"category_scores_gemma":[0.0002221078,0.0003755299,0.0006494264,0.0003852665,0.0004483896,0.000433239,0.0005371,0.001673388,0.0007593626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006707876,"about_ca_system_score_gemma":0.0002574506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006178507,"about_ca_topic_score_gemma":0.0008980873,"domain_scores_codex":[0.9993611,0.0001428552,0.00005926401,0.0001293008,0.0001804943,0.0001270528],"domain_scores_gemma":[0.999556,0.00006392533,0.0001169971,0.00006386318,0.00002367237,0.0001754359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002593692,0.0002763702,0.0002869606,0.00002891876,0.00001342958,0.0001942263,0.00001834619,0.000103198,0.9976352,0.0001836505,0.00009605533,0.0009042386],"study_design_scores_gemma":[0.0001299321,0.002220419,0.002156493,0.00001421987,0.0000505724,0.001022519,0.00003506116,0.001799454,0.9896122,0.0001003673,0.002849656,0.000009089114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898386,0.001350689,0.004356219,0.0003254674,0.00009248826,0.0002114591,0.0009018595,0.000418382,0.002504783],"genre_scores_gemma":[0.9897503,0.001018915,0.003044923,0.0001620367,0.00004379863,0.0002382882,0.0008939938,0.00008963153,0.004758155],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001582581,"threshold_uncertainty_score":0.005294323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109937402986339,"score_gpt":0.2076596029204307,"score_spread":0.1966658626217968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}