{"id":"W2551042557","doi":"10.1182/blood.v118.21.227.227","title":"Mutated EZH2 Collaborates with Myc in Inducing Lymphoma in a Mouse Model","year":2011,"lang":"en","type":"article","venue":"Blood","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Cancer Agency","funders":"","keywords":"EZH2; Lymphoma; Germinal center; Cancer research; Biology; Transgene; Follicular lymphoma; Genetically modified mouse; Spleen; Molecular biology; Immunology; B cell; Genetics; Antibody; Histone; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007264673,0.0001052989,0.0001006812,0.00008079536,0.00001602283,0.000007851055,0.00007523421,0.0001461264,0.000004631954],"category_scores_gemma":[0.00001504809,0.000102657,0.00001474486,0.0002575529,0.00002739904,0.000004786304,0.00003050708,0.00004253841,0.000002438429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002518965,"about_ca_system_score_gemma":0.0001801113,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002098942,"about_ca_topic_score_gemma":0.001704409,"domain_scores_codex":[0.999338,0.00002557896,0.000149181,0.0002478686,0.000064632,0.0001747883],"domain_scores_gemma":[0.9996665,0.000002261539,0.00005148731,0.0001938714,0.00005124339,0.00003466541],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002530715,0.000408365,0.02324753,0.00001207328,0.00004472804,0.00001219839,0.0007023848,0.008221759,0.9661509,0.00002145227,0.00002564213,0.0008998355],"study_design_scores_gemma":[0.003429574,0.00017057,0.01391187,0.00002745334,0.00001499233,0.00001086914,0.00008329075,0.003185126,0.9789255,0.0000434325,0.00002365401,0.0001737249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987713,0.0002688456,0.0001094675,0.00001324145,0.00001501818,0.0001646096,0.00001007805,0.00001167844,0.0006357464],"genre_scores_gemma":[0.998423,0.0000415962,0.001171347,0.00002841492,0.00002253368,0.00003103528,0.00004285375,0.0000221685,0.0002170483],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01277449,"threshold_uncertainty_score":0.4186231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0109937402986339,"score_gpt":0.2076596029204307,"score_spread":0.1966658626217968,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}