{"id":"W2551325974","doi":"10.1038/npjvaccines.2016.21","title":"In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine","year":2016,"lang":"en","type":"article","venue":"npj Vaccines","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"National Institutes of Health; National Institute of Allergy and Infectious Diseases; INOVIO Pharmaceuticals; Public Health Agency of Canada; University of Pennsylvania","keywords":"Zika virus; Virology; DNA vaccination; Biology; Immunology; Immune system; Immunity; Immunogen; Antibody; Virus; Interferon; Neutralizing antibody; Immunization; Medicine; Monoclonal antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002666581,0.0006014171,0.0003322762,0.0003021634,0.0001105408,0.0003359324,0.0003661872,0.0007230241,0.001515534],"category_scores_gemma":[0.0001621809,0.0001978902,0.000320579,0.0000903076,0.0003205974,0.0003014492,0.0001568106,0.001184596,0.0004388966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002892185,"about_ca_system_score_gemma":0.0001841321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003302081,"about_ca_topic_score_gemma":0.0002611995,"domain_scores_codex":[0.9998065,0.00003140458,0.00001283727,0.00004180121,0.00004214389,0.00006527871],"domain_scores_gemma":[0.9998784,0.00003412911,0.00003487115,0.0000168921,0.00001272707,0.00002291648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002316939,0.0002011698,0.00005981877,0.00004032776,0.000005712497,0.00001631083,0.00001747496,0.0001247744,0.9979296,0.0001091086,0.00002778504,0.001236253],"study_design_scores_gemma":[0.0001286076,0.007282125,0.001166426,0.00001671416,0.00002752134,0.0001572779,0.00002036068,0.001061298,0.9881704,0.00006995224,0.001894898,0.000004275041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927098,0.0009067188,0.004456523,0.000135778,0.00008627147,0.0001477799,0.0002491905,0.0001148703,0.00119309],"genre_scores_gemma":[0.9941753,0.0005519632,0.001879819,0.00005810658,0.00002701004,0.00009509564,0.0004296442,0.00001565995,0.002767399],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001515534,"threshold_uncertainty_score":0.005069971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007527500506667664,"score_gpt":0.247386181667978,"score_spread":0.2398586811613104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}