{"id":"W2551398945","doi":"10.1038/nrneurol.2016.166","title":"The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis Cooperative","year":2016,"lang":"en","type":"review","venue":"Nature Reviews Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":414,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital; University of Toronto; St. Michael's Hospital","funders":"National Institute of Neurological Disorders and Stroke; Medical Research Council","keywords":"Medicine; Multiple sclerosis; McDonald criteria; Statement (logic); Biomarker; Magnetic resonance imaging; Medical physics; Standardization; Clinical Practice; Radiology; Physical therapy; Computer science; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.006329698,0.0007190331,0.003414858,0.0001202529,0.0005222302,0.00005621742,0.0007270906,0.0003132487,0.0000153885],"category_scores_gemma":[0.04360952,0.0002847825,0.0008353622,0.0006553269,0.001444492,0.00005106226,0.0004408896,0.002201579,0.00001098767],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001624538,"about_ca_system_score_gemma":0.0005350717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002233839,"about_ca_topic_score_gemma":0.004262351,"domain_scores_codex":[0.9871894,0.00746404,0.002567118,0.001124992,0.0007494802,0.0009049895],"domain_scores_gemma":[0.9393378,0.05677128,0.001842422,0.001095775,0.0007590266,0.0001937012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000389836,0.0001533798,0.02799014,0.001030613,0.0004370396,0.000002607967,0.0001264852,0.000001466888,0.000007032125,0.000004899997,0.008469273,0.9613872],"study_design_scores_gemma":[0.00283119,0.0004884707,0.157794,0.00702258,0.001397836,0.000004668353,0.00004506692,0.0009767892,0.000003930779,0.000002411365,0.8291877,0.0002453698],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004195881,0.9668913,0.00001161867,0.009800052,0.0005313573,0.0175734,0.0009732007,0.00001826452,0.000004946681],"genre_scores_gemma":[0.0310023,0.9591235,0.00007893483,0.001436067,0.00048077,0.007687233,0.0001103822,0.00007479557,0.000006001821],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9611419,"threshold_uncertainty_score":0.9999604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2708616222812418,"score_gpt":0.4463352797925824,"score_spread":0.1754736575113406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}