{"id":"W2551416739","doi":"10.1111/febs.13966","title":"Regulation of kynurenine biosynthesis during influenza virus infection","year":2016,"lang":"en","type":"editorial","venue":"FEBS Journal","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":61,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University Medical Centre","funders":"Janssen Pharmaceuticals; Orionin Tutkimussäätiö; Jane ja Aatos Erkon Säätiö; Helsingin Yliopisto","keywords":"Virology; Biosynthesis; Kynurenine; Virus; Kynurenine pathway; Influenza A virus; Biology; Microbiology; Gene; Tryptophan; Biochemistry; Amino acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002772979,0.0002538722,0.0003380609,0.0004570163,0.0002452107,0.00009895286,0.0002850212,0.0005037471,0.0005650868],"category_scores_gemma":[0.004259607,0.0001965216,0.0002256341,0.0002482545,0.0001215495,0.0003675862,0.00006400414,0.0006713255,0.00007967107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000141282,"about_ca_system_score_gemma":0.0001802017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002095661,"about_ca_topic_score_gemma":0.00001604379,"domain_scores_codex":[0.997742,0.0002095998,0.0005610525,0.0003166191,0.0008719583,0.0002987697],"domain_scores_gemma":[0.9980333,0.0005692127,0.0008772216,0.0002475739,0.0001657266,0.0001069096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001949499,0.0000482045,0.00007045759,0.00006058758,0.00001658017,0.000008047705,0.0000540113,0.00001519532,0.6407462,0.00001777677,0.3562337,0.002534326],"study_design_scores_gemma":[0.001083083,0.0000984153,0.004658704,0.0004516618,0.00002742962,0.00004316386,0.000002794264,0.000004228642,0.5423914,0.0007224823,0.4502411,0.0002755325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.1899092,0.0001219873,0.0001858186,0.00007474349,0.80839,0.0001492597,0.0001194528,0.00007943625,0.000970179],"genre_scores_gemma":[0.1201086,0.001398008,0.00004790399,0.00003744036,0.8769121,0.000006218641,0.000005245498,0.0000800156,0.00140441],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.09835477,"threshold_uncertainty_score":0.8013918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01703207129280499,"score_gpt":0.279003416515174,"score_spread":0.261971345222369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}