{"id":"W2551581358","doi":"10.1016/j.bcmd.2016.11.009","title":"GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes","year":2016,"lang":"en","type":"article","venue":"Blood Cells Molecules and Diseases","topic":"Iron Metabolism and Disorders","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Health and Medical Research Council; U.S. Department of Veterans Affairs","keywords":"Phlebotomy; Internal medicine; Medicine; Odds ratio; Ferritin; Serum iron; Hemochromatosis; Cirrhosis; Gastroenterology; Endocrinology; Anemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008941457,0.0002976128,0.0004091543,0.0001764206,0.00007515924,0.00004220245,0.0001016825,0.0001185568,0.0002773369],"category_scores_gemma":[0.0001551427,0.0001887986,0.00009422927,0.0001866062,0.0001739756,0.0001225819,0.00006354976,0.00009222424,0.00001790105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002099671,"about_ca_system_score_gemma":0.000147618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002852652,"about_ca_topic_score_gemma":0.0001084176,"domain_scores_codex":[0.9983444,0.0001011202,0.0002559579,0.0004689501,0.0004056539,0.0004239275],"domain_scores_gemma":[0.9990017,0.0001385371,0.0001076514,0.0003005288,0.00006508388,0.0003864613],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001916294,0.003150082,0.9534096,0.000370321,0.0001636242,0.0008164364,0.0002865842,0.000002387604,0.02767465,0.0002264284,0.004148364,0.007835266],"study_design_scores_gemma":[0.01645605,0.0006101151,0.9604216,0.0005425913,0.001220069,0.00001873931,0.0004067929,0.00001111148,0.0187695,0.000298023,0.0006799513,0.0005654377],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901989,0.00733962,0.00002616339,0.0004066325,0.00004089923,0.0003705578,0.0002479871,0.00006940417,0.001299859],"genre_scores_gemma":[0.9966467,0.001077431,0.00009912356,0.001113262,0.00005111882,0.00003087154,0.0000550458,0.00004389808,0.0008825649],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01453976,"threshold_uncertainty_score":0.7698984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003878866673470402,"score_gpt":0.1964029612273589,"score_spread":0.1925240945538885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}