{"id":"W2551684983","doi":"10.1182/blood.v112.11.520.520","title":"Genome-Wide Expression Profiling Predicts Treatment Outcome in Classical Hodgkin Lymphoma","year":2008,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency","funders":"","keywords":"Medicine; Internal medicine; Oncology; Univariate analysis; Lymphoma; International Prognostic Index; Progression-free survival; Gene expression profiling; Immunohistochemistry; CD20; Rituximab; Diffuse large B-cell lymphoma; Logistic regression; Pathology; Multivariate analysis; Chemotherapy; Gene expression; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002599509,0.0001272569,0.0002013575,0.0003786751,0.00009283053,0.000290511,0.00009895927,0.0001835506,0.0007713175],"category_scores_gemma":[0.000695191,0.00006945345,0.0001115843,0.0003952056,0.00013578,0.00009622905,0.0001493766,0.0001539947,0.0001438483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009723457,"about_ca_system_score_gemma":0.00007732294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005071345,"about_ca_topic_score_gemma":0.0007238204,"domain_scores_codex":[0.9998995,0.00003012949,0.000007463762,0.00002741368,0.00001758331,0.00001777389],"domain_scores_gemma":[0.9997382,0.0001327952,0.00006106632,0.00001522421,0.00002188871,0.00003080983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004306366,0.00003370865,0.976919,0.00002102989,0.00006678604,0.000101283,0.0000309274,0.0004095626,0.01302319,0.00001765758,0.0001792088,0.008766945],"study_design_scores_gemma":[0.000008026789,0.00006453414,0.9962338,0.000003243825,0.00003795236,0.0002380754,0.0000453999,0.001800781,0.001351885,0.00005936637,0.000154878,0.000002202928],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992425,0.0002618188,0.0002117021,0.00002150608,0.000001661969,0.00000204151,0.0001520823,0.000005890149,0.0001008257],"genre_scores_gemma":[0.999448,0.00005935078,0.0001530078,0.00001208485,0.000003990904,0.000002044959,0.0002715579,0.000001519084,0.00004866044],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007713175,"threshold_uncertainty_score":0.002580285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03628988350224209,"score_gpt":0.2729385662410259,"score_spread":0.2366486827387838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}