{"id":"W2552031419","doi":"10.1038/nmicrobiol.2016.216","title":"The genome of Onchocerca volvulus, agent of river blindness","year":2016,"lang":"en","type":"article","venue":"Nature Microbiology","topic":"Parasitic Diseases Research and Treatment","field":"Medicine","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; McGill University","funders":"Biotechnology and Biological Sciences Research Council; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto; Compute Canada; Wellcome Trust","keywords":"Onchocerca volvulus; Onchocerciasis; Biology; Wolbachia; Tropical disease; Genome; Nematode; Disease; Volvulus; Drug development; Drug discovery; Proteome; Gene; Genetics; Evolutionary biology; Computational biology; Immunology; Bioinformatics; Drug; Medicine; Ecology; Pharmacology; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001122923,0.00008896055,0.0002336003,0.00005831508,0.00003257094,0.000001321744,0.0001355787,0.0001771686,0.0001620792],"category_scores_gemma":[0.0001484661,0.00003822646,0.0001134789,0.00008711245,0.0004645293,0.00001186986,0.00005333731,0.0001371794,0.000052479],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006867723,"about_ca_system_score_gemma":0.0001609288,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001293677,"about_ca_topic_score_gemma":0.000009106107,"domain_scores_codex":[0.9992939,0.00006298201,0.0001776206,0.0001544327,0.00007123333,0.0002397843],"domain_scores_gemma":[0.9991695,0.0001923232,0.00007280792,0.0002945172,0.0001812574,0.00008957438],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000965592,0.0004107644,0.01610967,0.00004464162,0.0004543864,0.00003681083,0.00006154196,1.809565e-7,0.9677042,0.0007646097,0.002478165,0.01096947],"study_design_scores_gemma":[0.008850855,0.002069102,0.3978228,0.0001973879,0.0003157661,0.0002126901,0.00006330942,0.000001680044,0.3206843,0.0006033877,0.2689776,0.0002011974],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877286,0.008705762,0.00003963932,0.001557636,0.0001524372,0.0003077167,0.0002606361,0.000009166389,0.001238414],"genre_scores_gemma":[0.9972244,0.0004655414,0.000110833,0.0001223818,0.0000490015,0.000009188431,0.00004182182,0.000007047514,0.001969777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6470199,"threshold_uncertainty_score":0.1774653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008315151295839405,"score_gpt":0.3039212564365373,"score_spread":0.2956061051406979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}