{"id":"W2552110041","doi":"10.1182/blood.v124.21.2112.2112","title":"Impact of Renal Impairment (RI) on Outcomes after Treatment (Tx) with Lenalidomide and Low-Dose Dexamethasone (Rd) in Newly Diagnosed Multiple Myeloma (NDMM) Patients (Pts): First Trial Results","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal; Ottawa Hospital; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Lenalidomide; Multiple myeloma; Renal function; Internal medicine; Thalidomide; Melphalan; Urology; Creatinine; Dialysis; Surgery; Gastroenterology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002042564,0.0007412063,0.001677108,0.0002052232,0.000243643,0.0008780516,0.0006955466,0.0007414716,0.003060216],"category_scores_gemma":[0.001951853,0.0002323982,0.002094392,0.0003022225,0.0005082897,0.0005484348,0.0003574653,0.002219916,0.0003410256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008304964,"about_ca_system_score_gemma":0.0008584559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005202888,"about_ca_topic_score_gemma":0.001305418,"domain_scores_codex":[0.999303,0.0004258507,0.00005264841,0.00008903517,0.00005335208,0.00007613467],"domain_scores_gemma":[0.9985548,0.0004992311,0.0004394655,0.0001043874,0.0000599025,0.0003422361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9417295,0.005547165,0.005120848,0.0007457639,0.002628451,0.00003536352,0.00005405163,0.0006840549,0.002699402,0.0000663629,0.000726476,0.03996267],"study_design_scores_gemma":[0.6350768,0.3287081,0.02568088,0.0001799096,0.004648095,0.0001992284,0.00004890691,0.001081592,0.002065422,0.0002654304,0.002014619,0.00003109276],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9901855,0.006609803,0.0002397969,0.0004033248,0.00008401751,0.0006135798,0.0007449877,0.0000273632,0.001091626],"genre_scores_gemma":[0.995104,0.001767532,0.0004147737,0.0003005486,0.0001795788,0.0006674064,0.000672913,0.000006301893,0.0008870143],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003060216,"threshold_uncertainty_score":0.01080221,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01653517012503599,"score_gpt":0.2859744430745613,"score_spread":0.2694392729495254,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}