{"id":"W2552242970","doi":"10.1016/j.ekir.2016.11.002","title":"Extreme Renal Pathology in Alagille Syndrome","year":2016,"lang":"en","type":"article","venue":"Kidney International Reports","topic":"Pediatric Hepatobiliary Diseases and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital","funders":"","keywords":"Alagille syndrome; JAG1; Medicine; Kidney; Pathology; Renal dysplasia; Cholestasis; Dysplasia; Desmin; Notch signaling pathway; Internal medicine; Immunohistochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003354939,0.0005062384,0.000468575,0.001491926,0.0006398046,0.0006600278,0.0006110948,0.001266537,0.003064323],"category_scores_gemma":[0.001393015,0.0002621363,0.0002923963,0.000679094,0.0007422667,0.0004787792,0.0009743701,0.0008547926,0.0004669244],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003461579,"about_ca_system_score_gemma":0.0004811188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001019553,"about_ca_topic_score_gemma":0.0008015617,"domain_scores_codex":[0.9996358,0.00004716247,0.00003680822,0.00007300195,0.0001296173,0.00007756697],"domain_scores_gemma":[0.9995311,0.0001415814,0.0001225278,0.00003466801,0.00004371227,0.0001264509],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.0001269528,0.00004352308,0.04155285,0.0002125742,0.00004615346,0.9011927,0.000396228,0.0005852358,0.02903099,0.002619792,0.001375669,0.02281735],"study_design_scores_gemma":[0.00001406396,0.00003367709,0.0266914,0.00005005412,0.00003692495,0.9644948,0.00008529691,0.0004476559,0.003709159,0.001700255,0.002718825,0.00001789568],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9358608,0.01213441,0.01257726,0.001768658,0.0001807185,0.00008217082,0.0003075234,0.001055493,0.03603294],"genre_scores_gemma":[0.9945247,0.001241948,0.002684147,0.0004177464,0.0001419137,0.000007198254,0.0000818573,0.00003162695,0.0008688045],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003064323,"threshold_uncertainty_score":0.01025122,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0171472907588955,"score_gpt":0.2700891288386237,"score_spread":0.2529418380797283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}