{"id":"W2552264335","doi":"10.1038/srep37324","title":"YY1 binding association with sex-biased transcription revealed through X-linked transcript levels and allelic binding analyses","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"RIKEN; University of British Columbia; BC Children's Hospital; Children's Hospital Foundation; Ministry of Education, Culture, Sports, Science and Technology; Child and Family Research Institute; Canadian Institutes of Health Research; Genome Canada","keywords":"Biology; Dosage compensation; Gene; Genetics; Transcription (linguistics); Gene silencing; Allele; YY1; Transcription factor; In silico; X chromosome; X-inactivation; Exon; Gene expression; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000172552,0.0001769532,0.0001985916,0.0003880583,0.000161181,0.0003095466,0.0001092524,0.0001361405,0.003557818],"category_scores_gemma":[0.0002953829,0.0001246446,0.0003080651,0.0003324905,0.0001138791,0.00008540414,0.0002223691,0.0001969616,0.0006235018],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001187457,"about_ca_system_score_gemma":0.0001152143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001443422,"about_ca_topic_score_gemma":0.002741479,"domain_scores_codex":[0.9998386,0.00001272653,0.00001139277,0.00007707621,0.00003410325,0.0000260425],"domain_scores_gemma":[0.9998419,0.00004876005,0.00005317944,0.00001165502,0.00001982932,0.00002473041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004249011,0.00001428109,0.08126847,0.0001971229,0.00008458774,0.0001929455,0.00010975,0.0003492178,0.909768,0.0001374115,0.0003343904,0.007118881],"study_design_scores_gemma":[0.00001689836,0.0001380601,0.7094368,0.00002087947,0.0001223573,0.00102669,0.0001444121,0.004149716,0.2798846,0.000213198,0.004819435,0.00002688115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910131,0.0009680419,0.002702025,0.00003324584,0.00001121062,0.000006922302,0.004657906,0.00004674834,0.0005608054],"genre_scores_gemma":[0.99014,0.0003634959,0.002128647,0.00003701068,0.000007478348,0.00001562046,0.005859655,0.00002920062,0.001418895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003557818,"threshold_uncertainty_score":0.01190215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04489501602333203,"score_gpt":0.3014282442667682,"score_spread":0.2565332282434362,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}