{"id":"W2552510069","doi":"10.1182/blood.v124.21.92.92","title":"Apolipoprotein Α-IV Is a Novel Ligand of Platelet αIIbβ3 Integrin and an Endogenous Thrombosis Inhibitor: Measurement of Single-Molecular Interactions By Biomembrane Force Probe","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; Canadian Blood Services; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Integrin; Platelet; Hemostasis; Platelet activation; Platelet Glycoprotein GPIIb-IIIa Complex; Chemistry; Integrin alpha M; Chinese hamster ovary cell; Cell biology; Biology; Biochemistry; Molecular biology; Receptor; Immunology; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001463276,0.0002598584,0.0001596324,0.0002353673,0.0001773152,0.0002094069,0.0002853149,0.000499273,0.0005975509],"category_scores_gemma":[0.0001618478,0.000111747,0.0001346168,0.0001737185,0.0001260235,0.0001577673,0.0001290827,0.0003826988,0.0001663843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000219634,"about_ca_system_score_gemma":0.00008616984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004687081,"about_ca_topic_score_gemma":0.0004817432,"domain_scores_codex":[0.9998438,0.00003444621,0.000007033138,0.00004266174,0.00004685842,0.00002520084],"domain_scores_gemma":[0.9999309,0.00002280866,0.00001511476,0.000004155722,0.00001173232,0.00001536292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002375962,0.00001295898,0.0001204713,0.00001121088,0.000002720548,0.0000187953,0.000005432564,0.00001320339,0.9991755,0.00002442334,0.00002494712,0.0005666228],"study_design_scores_gemma":[0.0000189949,0.000249274,0.005967617,0.000006245387,0.00002068349,0.0003185621,0.00002696676,0.00385442,0.9876995,0.00008237431,0.001747875,0.000007522613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9824558,0.00346699,0.0120637,0.0002327866,0.00005147952,0.00003425079,0.0001365553,0.00006011016,0.001498211],"genre_scores_gemma":[0.9843158,0.001132442,0.01098201,0.0001174399,0.00002919134,0.00007551372,0.0002778945,0.00001271203,0.003056908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005975509,"threshold_uncertainty_score":0.001998961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03411877600800155,"score_gpt":0.2574819560384101,"score_spread":0.2233631800304086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}