{"id":"W2552594981","doi":"10.1182/blood.v110.11.2598.2598","title":"Mesenchymal Stromal Cells Genetically Engineered To Overexpress Insulin-Like Growth Factor-1 Provide Paracrine Support for Cell-Based Erythropoietin Therapy of Chronic Renal Failure-Induced Anemia.","year":2007,"lang":"en","type":"article","venue":"Blood","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University; Jewish General Hospital","funders":"","keywords":"Erythropoietin; Mesenchymal stem cell; Medicine; Paracrine signalling; Cell therapy; Bone marrow; Stromal cell; Growth factor; Progenitor cell; Cancer research; Population; Genetic enhancement; Immunology; Internal medicine; Endocrinology; Biology; Stem cell; Cell biology; Pathology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001527715,0.0003307286,0.0002327936,0.0002723623,0.00008864274,0.0002367903,0.0001610495,0.0002169166,0.0008884298],"category_scores_gemma":[0.0000703213,0.0001061423,0.0002555811,0.0001239087,0.0002254436,0.0001483692,0.0001209769,0.0005564717,0.0002222749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000137431,"about_ca_system_score_gemma":0.000193101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003736235,"about_ca_topic_score_gemma":0.000857024,"domain_scores_codex":[0.999889,0.00001650916,0.00001027905,0.00001519918,0.00004284691,0.00002620788],"domain_scores_gemma":[0.9998811,0.00001532684,0.0000403782,0.00001132382,0.000007984996,0.00004376266],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001313162,0.00007904891,0.0001830281,0.00002139557,0.000004741514,0.00003700763,0.000009801026,0.00005576763,0.9980872,0.00006373317,0.00002983518,0.001297065],"study_design_scores_gemma":[0.00006633733,0.00144402,0.003049639,0.000006055433,0.00003897915,0.0002813533,0.00002076567,0.001089195,0.9917253,0.00003221739,0.002241537,0.000004540515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964664,0.000636659,0.001821611,0.00006174138,0.00004502777,0.00003304545,0.0001834905,0.00006081628,0.0006911426],"genre_scores_gemma":[0.9951512,0.0004710227,0.002659176,0.0000269054,0.000016844,0.00002958219,0.0002090113,0.0000106495,0.001425666],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008884298,"threshold_uncertainty_score":0.002972126,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02139884013987086,"score_gpt":0.2890840768027099,"score_spread":0.2676852366628391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}