{"id":"W2552805369","doi":"10.1016/j.bbamcr.2016.10.015","title":"Sirtuin 5 protects mitochondria from fragmentation and degradation during starvation","year":2016,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Moncton","funders":"Seventh Framework Programme; Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation; Fondation de la recherche en santé du Nouveau-Brunswick; Université de Moncton","keywords":"Mitochondrial fission; Cell biology; Mitochondrion; Mitophagy; Sirtuin; Biology; DNM1L; Autophagy; DNAJA3; ATP–ADP translocase; mitochondrial fusion; Biochemistry; Mitochondrial DNA; NAD+ kinase; Enzyme; Inner mitochondrial membrane; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002538128,0.0003287732,0.0003908001,0.0002573505,0.0002910985,0.0004380849,0.0002855329,0.0003446126,0.001574295],"category_scores_gemma":[0.0002260164,0.0002439512,0.0005396925,0.0001634203,0.0002905448,0.0003109337,0.000338852,0.0005437492,0.0003168653],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004372444,"about_ca_system_score_gemma":0.0003604567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001232133,"about_ca_topic_score_gemma":0.002187242,"domain_scores_codex":[0.9998362,0.00002277685,0.0000195223,0.00003051981,0.00002561337,0.00006529043],"domain_scores_gemma":[0.9998395,0.00001446123,0.00004436252,0.00002769411,0.00002117685,0.00005267396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002936051,0.00004247868,0.0009151158,0.00006966341,0.00004678019,0.00008187535,0.00003508058,0.00004986769,0.9936101,0.00008534826,0.0001369447,0.001990731],"study_design_scores_gemma":[0.0001311136,0.001007496,0.03303377,0.00001644393,0.00008974977,0.0004907933,0.0001370454,0.0007744411,0.9613736,0.0001572707,0.002769203,0.00001907189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945496,0.00326865,0.0009834148,0.000206398,0.00009298899,0.000009779689,0.000304594,0.00007462881,0.0005099375],"genre_scores_gemma":[0.9973151,0.0003982262,0.0003748127,0.00007184637,0.00001157614,0.000007566386,0.0004612195,0.0000109614,0.001348705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001574295,"threshold_uncertainty_score":0.005266607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02503114357524256,"score_gpt":0.2972459000800212,"score_spread":0.2722147565047786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}