{"id":"W2552834564","doi":"10.1111/mmi.13578","title":"Extensive functional redundancy in the regulation of <scp><i>C</i></scp><i>andida albicans</i> drug resistance and morphogenesis by lysine deacetylases <scp>H</scp>os2, <scp>H</scp>da1, <scp>R</scp>pd3 and <scp>R</scp>pd31","year":2016,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; Morphogenesis; Lysine; Candida albicans; Genetics; Cell biology; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.002114639,0.001538722,0.002384427,0.0006991645,0.0006502661,0.0001512762,0.000837456,0.001189758,0.00003263382],"category_scores_gemma":[0.01284175,0.001190972,0.0006723305,0.001520775,0.00251576,0.0004669244,0.0004792363,0.001028668,0.00008839574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003909103,"about_ca_system_score_gemma":0.0005896437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002383504,"about_ca_topic_score_gemma":0.0006400787,"domain_scores_codex":[0.9903499,0.001517566,0.002138723,0.002836616,0.0009023643,0.002254836],"domain_scores_gemma":[0.9850609,0.009624213,0.001340906,0.002112476,0.001219853,0.0006416754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000080907,0.0005244382,0.0184244,0.0004090106,0.0004537718,0.000197892,0.001691906,0.00002052106,0.7829897,0.0005013982,0.1943974,0.000308675],"study_design_scores_gemma":[0.008224334,0.0009008575,0.09646316,0.001070827,0.001060365,0.0007749623,0.007366297,0.00004193325,0.5374431,0.001784547,0.3446276,0.0002420043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9566169,0.03258148,0.002968926,0.0007970873,0.0004863257,0.002032796,0.0009888567,0.0001849628,0.003342714],"genre_scores_gemma":[0.963438,0.003653665,0.001239875,0.003070821,0.0003556211,0.0002285808,0.001099817,0.0002488192,0.02666485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2455465,"threshold_uncertainty_score":0.9997361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007527089161006162,"score_gpt":0.2173719970953824,"score_spread":0.2098449079343762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}