{"id":"W2552834564","doi":"10.1111/mmi.13578","title":"Extensive functional redundancy in the regulation of <scp><i>C</i></scp><i>andida albicans</i> drug resistance and morphogenesis by lysine deacetylases <scp>H</scp>os2, <scp>H</scp>da1, <scp>R</scp>pd3 and <scp>R</scp>pd31","year":2016,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; Morphogenesis; Lysine; Candida albicans; Genetics; Cell biology; Amino acid; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001371443,0.0003578197,0.0002242882,0.0002446157,0.0001953477,0.0004310589,0.0002807006,0.0002155251,0.0008917783],"category_scores_gemma":[0.0001335976,0.0001708407,0.0003797605,0.0001955803,0.0002407969,0.0001547004,0.0002520728,0.0004086876,0.0003381552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004049861,"about_ca_system_score_gemma":0.0003989732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00114516,"about_ca_topic_score_gemma":0.001505091,"domain_scores_codex":[0.9997793,0.00002121907,0.00002413856,0.00006000914,0.00007363681,0.00004164727],"domain_scores_gemma":[0.999805,0.00002222016,0.00006889498,0.00004038109,0.00002408032,0.00003946241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003725493,0.000006545379,0.0001983657,0.000012407,0.000004533427,0.00002986145,0.000003666173,0.00005036503,0.9988688,0.00006938909,0.00001583584,0.0007028923],"study_design_scores_gemma":[0.00001148152,0.0001374431,0.02255016,0.000004470503,0.00002437422,0.0005929737,0.00001978675,0.001060571,0.9737005,0.00008354545,0.001805635,0.000009077127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942332,0.001100783,0.002541897,0.00008873049,0.00001484529,0.00001521689,0.0005677579,0.0001300554,0.001307533],"genre_scores_gemma":[0.9973292,0.0002984502,0.001050683,0.00003413009,0.000004659003,0.00001114066,0.0006763733,0.00001885459,0.0005765377],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00114516,"threshold_uncertainty_score":0.002983272,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007527089161006162,"score_gpt":0.2173719970953824,"score_spread":0.2098449079343762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}