{"id":"W2553097248","doi":"10.1038/srep37479","title":"Genome mining unveils widespread natural product biosynthetic capacity in human oral microbe Streptococcus mutans","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University","funders":"Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Streptococcus mutans; Genome; Natural product; Biology; Computational biology; Microbiology; Genetics; Gene; Bacteria; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003053475,0.0003117824,0.0005115594,0.001761314,0.0003292641,0.0008437647,0.0001779982,0.0003320948,0.0007718391],"category_scores_gemma":[0.0008558787,0.000148832,0.0004695679,0.002245679,0.0001767758,0.00041284,0.0005552148,0.0003741341,0.0003262905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001694662,"about_ca_system_score_gemma":0.0004899452,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001167897,"about_ca_topic_score_gemma":0.002132766,"domain_scores_codex":[0.999745,0.00003509457,0.00002658731,0.00008068939,0.00007723174,0.00003539932],"domain_scores_gemma":[0.9996386,0.0001168245,0.00009379956,0.00004146198,0.00006688405,0.00004249427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001420676,0.0001959217,0.1617826,0.001580795,0.0003548902,0.001661741,0.0008491943,0.001366506,0.6702901,0.000669208,0.002321438,0.157507],"study_design_scores_gemma":[0.00005743027,0.0008546747,0.7994511,0.0002807644,0.00102977,0.007077402,0.002521093,0.008261141,0.1217111,0.002249458,0.0564172,0.00008890445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812559,0.006345429,0.002876017,0.0003594726,0.00002385193,0.00002804179,0.007310028,0.0001770809,0.001624116],"genre_scores_gemma":[0.966347,0.003651749,0.01301676,0.000160667,0.00003978832,0.0000245077,0.01607695,0.00004848839,0.0006341765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001761314,"threshold_uncertainty_score":0.002582073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0283072016891566,"score_gpt":0.2554082495988413,"score_spread":0.2271010479096847,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}