{"id":"W2553122372","doi":"10.4238/gmr15048934","title":"Identifying potential PARIS homologs in D. melanogaster","year":2016,"lang":"en","type":"article","venue":"Genetics and Molecular Research","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland; Parkinson Society Canada","keywords":"Drosophila melanogaster; Parkin; RNA interference; Biology; PINK1; Cell biology; Gene; Phenotype; Genetics; Melanogaster; Programmed cell death; Gene silencing; Mitochondrion; Gene expression; Autophagy; RNA; Parkinson's disease; Mitophagy; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003431482,0.00009152141,0.0001360072,0.0001745826,0.0001184721,0.00006953756,0.000102557,0.0000733747,0.00009902911],"category_scores_gemma":[0.00004729004,0.00006194771,0.0000434363,0.0001060694,0.0002356006,0.00003269914,0.0002711495,0.0001539668,0.00006890213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004247421,"about_ca_system_score_gemma":0.00009012865,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009494559,"about_ca_topic_score_gemma":0.000008570808,"domain_scores_codex":[0.9983268,0.000125696,0.0001295932,0.0003141124,0.0005839275,0.000519849],"domain_scores_gemma":[0.9991696,0.00002865391,0.00001585417,0.0003409106,0.0001174981,0.0003274243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0008387248,0.0009389268,0.347821,0.0001529516,0.002500721,0.008452785,0.0001299063,5.187151e-7,0.5500689,0.0003881672,0.005127144,0.08358018],"study_design_scores_gemma":[0.02000753,0.00260696,0.5101199,0.0006292755,0.0003226697,0.0002769458,0.000306345,0.0002260242,0.4499489,0.009333437,0.005591099,0.0006308962],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.981192,0.01519089,0.0003444697,0.002088549,0.00001927535,0.00035537,0.00001634669,0.000006975108,0.0007861344],"genre_scores_gemma":[0.9952073,0.004160995,0.0002652328,0.00004929092,0.00002291994,0.00003880776,0.000009640865,0.00002020245,0.0002256843],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1622989,"threshold_uncertainty_score":0.2526155,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05596866520013048,"score_gpt":0.3898855366457767,"score_spread":0.3339168714456462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}