{"id":"W2553122372","doi":"10.4238/gmr15048934","title":"Identifying potential PARIS homologs in D. melanogaster","year":2016,"lang":"en","type":"article","venue":"Genetics and Molecular Research","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Memorial University of Newfoundland; Parkinson Society Canada","keywords":"Drosophila melanogaster; Parkin; RNA interference; Biology; PINK1; Cell biology; Gene; Phenotype; Genetics; Melanogaster; Programmed cell death; Gene silencing; Mitochondrion; Gene expression; Autophagy; RNA; Parkinson's disease; Mitophagy; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006238388,0.0004394819,0.0001797231,0.0006679612,0.0002579024,0.0002654549,0.0002840009,0.0004405695,0.001979326],"category_scores_gemma":[0.00009316343,0.000199123,0.0004096184,0.0003156129,0.0001543626,0.0001208145,0.0002346006,0.0003581799,0.001085899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007308003,"about_ca_system_score_gemma":0.0002176013,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003105866,"about_ca_topic_score_gemma":0.005806326,"domain_scores_codex":[0.9999145,0.000004839936,0.00001228913,0.00003454692,0.00002265839,0.00001109793],"domain_scores_gemma":[0.9999185,0.00001253042,0.00002980623,0.000007280636,0.00001222719,0.00001968276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007517987,0.00001380267,0.001332396,0.00005505666,0.00000813813,0.0003006022,0.00002841449,0.00009710671,0.9950308,0.000128987,0.0001600782,0.002769391],"study_design_scores_gemma":[0.00008558549,0.0004146247,0.09109503,0.00004655519,0.0001070942,0.00360644,0.0002927046,0.002327051,0.8516846,0.0001721523,0.05012274,0.00004543491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9718843,0.002232081,0.00683665,0.0002676905,0.00005199873,0.0002116871,0.01224158,0.0003391859,0.005934756],"genre_scores_gemma":[0.9318098,0.00174885,0.01787621,0.0003872342,0.00001676742,0.0001587765,0.03349979,0.0001380184,0.0143645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003105866,"threshold_uncertainty_score":0.00662148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05596866520013048,"score_gpt":0.3898855366457767,"score_spread":0.3339168714456462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}