{"id":"W2553518536","doi":"10.1038/ncb3436","title":"SCAI promotes DNA double-strand break repair in distinct chromosomal contexts","year":2016,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Arbejdstilsynet; Canadian Institutes of Health Research; Medical Research Council; Novo Nordisk; Canada Research Chairs; National Institutes of Health; H. Lundbeck A/S; Lundbeckfonden; Sundhed og Sygdom, Det Frie Forskningsråd; Deutsche Forschungsgemeinschaft; Novo Nordisk Fonden; Kræftens Bekæmpelse","keywords":"Chromatin; Homologous recombination; Biology; Genome instability; DNA repair; Cell biology; DNA damage; DNA; Heterochromatin; Recombinase; Molecular biology; Histone; Genetics; Recombination; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003674736,0.0003448731,0.0003382149,0.0004292443,0.0003565819,0.001040128,0.0002980832,0.0005256838,0.002398761],"category_scores_gemma":[0.0003946908,0.0003757721,0.0003411993,0.0002511933,0.0004684839,0.0005202811,0.0006790328,0.001426202,0.0008307869],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005391098,"about_ca_system_score_gemma":0.0002537213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000615371,"about_ca_topic_score_gemma":0.001688104,"domain_scores_codex":[0.9996784,0.00004154628,0.00002307072,0.00008125017,0.00008600211,0.00008969317],"domain_scores_gemma":[0.999356,0.0001693822,0.0001221619,0.0001181621,0.00006048799,0.0001738308],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006801574,0.00001518605,0.0001689308,0.00001554133,0.00000359233,0.0000281471,0.00001081387,0.00003743847,0.9985052,0.0003528844,0.00004864413,0.0007456373],"study_design_scores_gemma":[0.00001673776,0.0000838055,0.004963234,0.00000609055,0.000009197981,0.0001476058,0.00002858895,0.000824718,0.9922328,0.0002098208,0.001471424,0.000005850558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841852,0.003354848,0.00738041,0.0003024907,0.0000840913,0.00002187016,0.000156106,0.0003631674,0.004151689],"genre_scores_gemma":[0.9943533,0.0006387656,0.002102076,0.00005607593,0.00002818204,0.00001226017,0.0001907315,0.0001041767,0.002514428],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002398761,"threshold_uncertainty_score":0.008024633,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004923724634771431,"score_gpt":0.2382603989731974,"score_spread":0.2333366743384259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}