{"id":"W2553564959","doi":"10.1038/ijosup.2016.5","title":"Cholecystokinin-induced satiety, a key gut servomechanism that is affected by the membrane microenvironment of this receptor","year":2016,"lang":"en","type":"review","venue":"International Journal of Obesity Supplements","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Université Laval; Mayo Clinic","keywords":"Ghrelin; Cholecystokinin; Cholecystokinin receptor; Allosteric modulator; Gastric emptying; Agonist; Endocrinology; Appetite; Internal medicine; Allosteric regulation; Receptor; Biology; Pharmacology; Hormone; Medicine; Stomach","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003377727,0.0004357778,0.001052852,0.0002043136,0.00009786093,0.00006990896,0.002212084,0.00014463,0.003709744],"category_scores_gemma":[0.00012544,0.0002561691,0.0007511461,0.000121195,0.0001095423,0.0002309308,0.0005546256,0.0005362974,0.0002236931],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002458964,"about_ca_system_score_gemma":0.0001209795,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002429193,"about_ca_topic_score_gemma":0.000001318856,"domain_scores_codex":[0.996361,0.000513969,0.001113111,0.0004367538,0.001244483,0.0003306894],"domain_scores_gemma":[0.9967204,0.0003377751,0.002360303,0.0003253252,0.0001376371,0.000118592],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008667987,0.0006037398,0.000016553,0.0005036118,0.0005701705,0.00006247321,0.000169863,1.417944e-7,0.8511313,0.0001509183,0.04029882,0.1064057],"study_design_scores_gemma":[0.0008043012,0.0003725851,0.00002248167,0.002627569,0.0001637443,0.0001977385,0.000009187207,5.304308e-7,0.1440632,0.00007600898,0.8514494,0.0002132319],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1831702,0.7712754,0.0001751967,0.006105266,0.01552549,0.005205005,0.01709119,0.0000889278,0.001363376],"genre_scores_gemma":[0.03507659,0.962621,0.00007187217,0.0009642923,0.0003403233,0.00001346357,0.00004358111,0.00005856133,0.0008103348],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8111506,"threshold_uncertainty_score":0.999989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05378742875616965,"score_gpt":0.3196114542260443,"score_spread":0.2658240254698746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}