{"id":"W2553678345","doi":"10.1016/j.ijrobp.2016.11.026","title":"Androgen Suppression Combined with Elective Nodal and Dose Escalated Radiation Therapy (the ASCENDE-RT Trial): An Analysis of Survival Endpoints for a Randomized Trial Comparing a Low-Dose-Rate Brachytherapy Boost to a Dose-Escalated External Beam Boost for High- and Intermediate-risk Prostate Cancer","year":2016,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":732,"is_retracted":false,"has_abstract":false,"ca_institutions":"Sunnybrook Health Science Centre; Health Sciences Centre; University of British Columbia; University of Toronto; BC Cancer Agency","funders":"","keywords":"Medicine; Clinical endpoint; Prostate cancer; Brachytherapy; Hazard ratio; Randomized controlled trial; Androgen deprivation therapy; Urology; Radiation therapy; Survival analysis; Androgen suppression; Progression-free survival; Internal medicine; Nuclear medicine; Oncology; Surgery; Cancer; Overall survival; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002246898,0.00191416,0.003102076,0.0004510741,0.0003932167,0.001138936,0.001345461,0.001258723,0.005386493],"category_scores_gemma":[0.002106925,0.0004466518,0.002888653,0.0004273223,0.001505103,0.001280531,0.00069806,0.004073549,0.0005659827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008483754,"about_ca_system_score_gemma":0.0008011388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001425224,"about_ca_topic_score_gemma":0.003072101,"domain_scores_codex":[0.9989837,0.0006827321,0.00003789057,0.0001501641,0.00004810233,0.00009747073],"domain_scores_gemma":[0.9989179,0.0003857274,0.0002138763,0.000130581,0.00003655393,0.0003153038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9821191,0.002401724,0.001046205,0.0002713782,0.00178644,0.00002210032,0.00004361365,0.001128437,0.001262162,0.000189297,0.0005567073,0.009172742],"study_design_scores_gemma":[0.9076948,0.07921803,0.006287345,0.00006284425,0.002925823,0.00006338452,0.00006889103,0.001457948,0.0005168121,0.0006730856,0.001001326,0.00002973179],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991113,0.003883912,0.0005508906,0.0005937043,0.0004415324,0.0005776362,0.0008949681,0.00009252241,0.001851824],"genre_scores_gemma":[0.992515,0.001487323,0.001026512,0.0006480125,0.0004604699,0.0007243459,0.001295284,0.00003070114,0.001812219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005386493,"threshold_uncertainty_score":0.01801962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01776587911076461,"score_gpt":0.333402815900654,"score_spread":0.3156369367898894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}